NCT01290588

Completed

Aqueous Humor Dynamics and Biometric Parameters in Eyes of C...

University of Nebraska Source

Other study identifiers

Sponsor study identifier

0364-09-FB

Study Type

observational

Actual enrollment (reported)

53

Locations

1 country

Sites

1

Timeline

Study Start

June 1, 2013

Actual (reported)

Primary Completion

March 25, 2022

Actual (reported)

Study Completion

March 25, 2022

Actual (reported)

Brief Summary

The purpose of this study is to determine the effect of age and ethnic background on ocular aqueous humor dynamics and biometric parameters. Data of normal healthy children and adults will be used as controls for future study of juvenile glaucoma, and diabetes and potentially for any other condition that affects intraocular pressure in children.

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: completed
Actual enrollment (reported): 53 participants
Study completion date: March 25, 2022
Actual (reported)
Listed locations: 1 countries · 1 sites

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

First Submitted
February 3, 2011
Actual (reported)
First Posted
February 7, 2011
Actual (reported)
Study Start
June 1, 2013
Actual (reported)
Primary Completion
March 25, 2022
Actual (reported)
Study Completion
March 25, 2022
Actual (reported)

Last Updated: September 29, 2023
Status Verified: September 2023
Last Update Submitted: September 27, 2023

Conditions

Healthy

Study Arms (4)

Children of Caucasian descent

Healthy children of Caucasian descent.

Adults of Caucasian descent

Healthy adult eyes of Caucasian descent.

Children of African-American descent

Healthy children of African-American descent.

Adults of African-American descent

Healthy adults of African-American descent.

Eligibility Criteria

Age15 Years - 50 Years

Sexall

Healthy VolunteersYes

Age GroupsChild (0-17), Adult (18-64)

Sampling MethodNon-Probability Sample

Study Population

* Children * Adults

You may qualify if:

Subjects must not have any ocular diseases

Sponsors & Collaborators

University of Nebraska
Otherlead

Study Sites (1)

University of Nebraska Medical Center, Department of Ophthalmology and Visual Sciences

Omaha, Nebraska, 68198-5540, United States

Study Officials

Carol B Toris, PhD
University of Nebraska
PRINCIPAL INVESTIGATOR

Enrollment

53 participants (actual enrollment reported by the registry).

Study Design

Study Type: observational
Observational Model: COHORT
Time Perspective: OTHER
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

February 3, 2011

First Posted

February 7, 2011

Study Start

June 1, 2013

Actual (reported)

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Children, 15 - 18 years of age

Adults, 30 - 50 years of age

You may not qualify if:

Women who are pregnant or lactating
Aphakia or pseudophakia
Chronic or recurrent severe ocular inflammatory disease.
Ocular infection or inflammation within three (3) months of screening visit.
History of clinically significant or progressive retinal disease such as retinal degeneration, diabetic retinopathy or retinal detachment.
Any abnormality preventing reliable tonometry of either eye.
History of any ocular pathology (including dry eye).
A cup-to-disc ratio greater than 0.8
History of intraocular surgery
History of ocular laser surgery
History of hypersensitivity or allergy to beta blockers and sulfa drugs.
History of severe, unstable or uncontrolled cardiovascular, hepatic or renal disease.
History of bronchial asthma or chronic obstructive pulmonary disease (COPD).
Inability to discontinue contact lens wear.
Diagnosis of ocular hypertension or glaucoma or any ocular disease

Contact the study team to confirm eligibility.

Primary Completion

March 25, 2022

Actual (reported)

Study Completion

March 25, 2022

Actual (reported)

Last Updated

September 29, 2023

Record last verified: 2023-09

Data Sharing

IPD Sharing: Will not share

Source record

Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.

Source: ClinicalTrials.gov.

JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.

Registry identifier: NCT01290588
Data provider: ClinicalTrials.gov
Source updated: 2023-09-29
Normalization version: ctgov-legacy-1

Open registry record

Source retrieved: 2026-10-25 22:38:57 UTC

Locations

US(1)

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Study Arms (4)

Children of Caucasian descent

Adults of Caucasian descent

Children of African-American descent

Adults of African-American descent

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations