Study of CPAP as Intervention After Lung Resection

NCT01285648 | Completed DMC

• 1 other identifier: ROCETO130682
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study was to compare the oxygenation index (OI), dyspnea, and pain scale and evaluate the duration of thoracic drainage and pleural air leaks after lung resection in two groups of patients: chest physiotherapy (CP) patients and combined CP and Continuous Positive Airway Pressure (CPAP) patients.

Conditions

Lung Cancer; Pulmonary Complications

Keywords

chest tubes,; Continuous Positive Airway Pressure,; lung resection, thoracic surgery,; noninvasive ventilation,; postoperative

Outcome Measures

Primary Outcomes (1)

• Bubbling drains

  From the immediate postoperative day until hospital discharge, the presence of chest tubes and the occurrence of air leaks in them as evidenced by the bubbling of the water seal were recorded. The maintenance and removal of drains or their use with wall suction were determined by applying the medical protocol of the institution through the analysis of X-rays and the amount of drained fluid.

  From immediate postoperative until fifth, along the study, in a total of one year

Secondary Outcomes (1)

• Pain score

  Reported pain score after lung resection, along the study, during one year

Study Arms (2)

Cpap

OTHER

This group joined chest physiotherapy with CPAP via nasal masks for two hours.CPAP was continued from the immediate postoperative day until the second postoperative day, twice a day.

Procedure: Cpap

Chest Physiotherapy

OTHER

Chest Physiotherapy consisted of bronchial hygiene techniques and pulmonary expansion, in addition to exercises, and received oxygen supplementation to maintain the pulse oxymetry saturations \> 90%.

Procedure: Cpap

Interventions

Cpap PROCEDURE

This study did not involved drugs. The Oxygenation index, Borg Scale, pain scale and the presence and duration of thoracic drainage was determined in the immediate postoperative (POi) period and in the first and second postoperative (PO1, PO2) days in 40 patients who underwent elective lung resection,in two groups of intervention: chest physiotherapy, and associate this with cpap

Also known as: Noninvasive ventilation, lung resection

Chest Physiotherapy; Cpap

Eligibility Criteria

• Age: 40 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• medical diagnosis of lung cancer and an indication for lung resection (lobectomy, bilobectomy and pneumonectomy) with posterolateral thoracotomy;
• aged between 40 and 75 years.

You may not qualify if:

• Patients who refused to participate in the survey;
• lung resection with incisions other than posterolateral;
• patients who had contraindications to the use of noninvasive ventilation.

Sponsors & Collaborators

• University of Campinas, Brazil: lead

Study Sites (1)

Campinas State University

Campinas, São Paulo, 13083887, Brazil

Location

Related Publications (1)

• Roceto Ldos S, Galhardo FD, Saad IA, Toro IF. Continuous positive airway pressure (CPAP) after lung resection: a randomized clinical trial. Sao Paulo Med J. 2014;132(1):41-7. doi: 10.1590/1516-3180.2014.1321525.

  PMID: 24474079 DERIVED

MeSH Terms

Conditions

Lung Neoplasms

Interventions

Continuous Positive Airway Pressure; Noninvasive Ventilation

Condition Hierarchy (Ancestors)

Respiratory Tract Neoplasms; Thoracic Neoplasms; Neoplasms by Site; Neoplasms; Lung Diseases; Respiratory Tract Diseases

Intervention Hierarchy (Ancestors)

Positive-Pressure Respiration; Respiration, Artificial; Airway Management; Therapeutics; Respiratory Therapy

Study Officials

• Lígia S. Roceto

  University of Campinas, Brazil

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: FACTORIAL
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: January 25, 2011
• First Posted: January 28, 2011
• Study Start: November 1, 2007
• Primary Completion: December 1, 2009
• Study Completion: February 1, 2010
• Last Updated: January 28, 2011

Record last verified: 2011-01

Locations

BR (1)