NCT01281410

Brief Summary

The study is a monocentric, controlled randomized trial. Its an interventional method study. There is a control and an interventional group. The interventional group is receiving a specific inspiratory muscle training with "Respifit" (special device for inspiratory muscle training) during the first 30 days after allogenic stem cell transplantation. The investigators want to show that the training group gets stronger inspiratory muscles. The investigators measure the change of PIMAX values and MVV values.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
106

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jan 2011

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2011

Completed
17 days until next milestone

First Submitted

Initial submission to the registry

January 18, 2011

Completed
6 days until next milestone

First Posted

Study publicly available on registry

January 24, 2011

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2013

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2013

Completed
Last Updated

July 4, 2011

Status Verified

November 1, 2010

Enrollment Period

2.1 years

First QC Date

January 18, 2011

Last Update Submit

June 30, 2011

Conditions

Keywords

respiratory muscleshematopoetic stem cell transplantationinspiratory muscle training

Outcome Measures

Primary Outcomes (2)

  • Change of PI max-value from baseline at 30 days after stem cell transplantation

    max strength of the inspiratory muscles

    baseline and 30 days after stem cell transplantation

  • Change of MVV-value from baseline at 30 days after transplantation

    max voluntary volume for Inspiratory muscle endurance

    baseline and 30 days after stem cell transplantation

Secondary Outcomes (2)

  • inpatient days

    from baseline to maximal 60 days after stem cell transplantation

  • Incidence of pneumonia

    from baseline to 30 days after stem cell transplantation

Study Arms (2)

Standard physiotherapy

NO INTERVENTION

Standard Physiotherapy without Inspiratory Muscle Training

Inspiratory muscle training

EXPERIMENTAL

Inspiratory muscle training with a device named Respifit in addition to the usual physiotherapy program

Procedure: Inspiratory Muscle TrainingOther: inspiratory muscle training

Interventions

Inspiratory Muscle Training with Respifit (5 times per week)

Inspiratory muscle training

Eligibility Criteria

Age17 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Patients receiving allogenic stem cell transplantation
  • Age 17 - 80 years old
  • Informed consent

You may not qualify if:

  • Actual pneumonia at the beginning of the trial
  • Impaired vision
  • Patient is not able to handle "Respifit"

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Elisabethinen Hospital

Linz, 4020, Austria

RECRUITING

Study Officials

  • Hanns Hauser, MD

    Elisabethinen Hospital

    STUDY CHAIR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

January 18, 2011

First Posted

January 24, 2011

Study Start

January 1, 2011

Primary Completion

February 1, 2013

Study Completion

February 1, 2013

Last Updated

July 4, 2011

Record last verified: 2010-11

Locations