Studies of Kidney Transplant Outcome

NCT01277770 | Completed

• 1 other identifier: 00011652
• Study Type: observational
• Target: 7,500
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to improve outcome for kidney transplant recipients. There has not been commensurate improvement in medium and long-term outcomes. Ongoing clinical research is necessary to improve transplant outcomes.

Conditions

Transplant Recipient (Kidney); Steroid-Free Maintenance Immunosuppression; Post-Transplant Infections; Thymoglobulin

Keywords

Thymoglobulin; Kidney Transplant Recipients; Steroid-Free; Immunosuppression

Outcome Measures

Primary Outcomes (1)

• Data Analysis

  All studies are analyses from the Transplant Outcomes Database. Recipients have signed consent to have medical information entered into the database for these analyses. The database contains information on short, medium and long-term results.

  10 year followup

Study Arms (1)

Kidney Transplant Recipients

Kidney Transplant Recipients at the University of Minnesota since 1984. The study looks at a 10 year followup of steroid-free maintenance immunosuppression, post-transplant infections and evaluation of the DGF nomogram in Thymoglobulin on patients at the University of Minnesota.

Drug: Steroid-Free Maintenance Immunosuppression; Other: Infection After Kidney Transplantation; Drug: Evaluation of the DGF nomogram in Thymoglobulin

Interventions

Steroid-Free Maintenance Immunosuppression DRUG

10 year follow-up of steroid-free maintenance immunosuppression

Also known as: Steroid-Free, Immunosuppression

Kidney Transplant Recipients

Infection After Kidney Transplantation OTHER

A cross-sectional study of infection after kidney transplantation (with emphasis on infection in steroid-free recipients).

Also known as: Infection, Transplantation, Steroid-Free

Kidney Transplant Recipients

Evaluation of the DGF nomogram in Thymoglobulin DRUG

An evaluation of the DGF nomogram in Thymoglobulin treated recipients at the University of Minnesota

Also known as: Thymoglobulin

Kidney Transplant Recipients

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Kidney transplant recipients at the University of Minnesota

You may qualify if:

• Kidney Transplant Recipient at the University of Minnesota
• Kidney Transplant Recipients on steroid-free maintenance immunosuppression

You may not qualify if:

• Non-kidney transplant patients at the University of Minnesota

Sponsors & Collaborators

• University of Minnesota: lead
• Genentech, Inc.: collaborator

Study Sites (1)

University Of Minnesota

Minneapolis, Minnesota, 55414, United States

Location

MeSH Terms

Interventions

Immunosuppression Therapy; Transplantation; thymoglobulin

Intervention Hierarchy (Ancestors)

Immunotherapy; Immunomodulation; Biological Therapy; Therapeutics; Immunologic Techniques; Investigative Techniques; Surgical Procedures, Operative

Study Officials

• Arthur Matas, MD

  University of Minnesota

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 19, 2010
• First Posted: January 17, 2011
• Study Start: May 1, 2009
• Primary Completion: May 6, 2019
• Study Completion: May 6, 2019
• Last Updated: May 15, 2019

Record last verified: 2019-05

Locations

US (1)