Glucose, Whey Protein and Time to the Next Meal on Mealtime Food Intake in Children

NCT01272427 | Completed

• 1 other identifier: FoodIntakeKids_21595
• Study Type: interventional
• Target: 36
• Locations: 1 country
• Sites: 1

Brief Summary

The investigators hypothesize that glucose and whey protein given 30 and 60 min before a pizza meal will exert different effects on food intake in adolescent children, and will depend on pubertal stage. Food intake will be measured at 30 and 60 min following a glucose(0.75 g of glucose/kg body weight), whey protein (0.75 g of glucose/kg body weight) or sweetened noncaloric beverage. Subjective appetite will be measured as well.

Conditions

Obesity

Outcome Measures

Primary Outcomes (1)

• Food intake (kcal)

  30 and 60 min after the treatment

Secondary Outcomes (1)

• subjective appetite

  0-120 min

Study Arms (6)

noncaloric beverage

EXPERIMENTAL

noncaloric sweetened beverage administered 30 min prior to mealtime

Dietary Supplement: water with noncaloric sweetener

noncaloric beverage (60 min)

EXPERIMENTAL

noncaloric sweetened beverage administered 60 min prior to mealtime

Dietary Supplement: water with noncaloric sweetener

glucose beverage

EXPERIMENTAL

glucose beverage administered 30 min prior to mealtime

Dietary Supplement: water with glucose

glucose beverage (60 min)

EXPERIMENTAL

glucose beverage administered 60 min prior to mealtime

Dietary Supplement: water with glucose

whey protein beverage

EXPERIMENTAL

whey protein beverage administered 30 min prior to mealtime

Dietary Supplement: water and whey protein

whey protein beverage (60 min)

EXPERIMENTAL

whey protein beverage administered 60 min prior to mealtime

Dietary Supplement: water and whey protein

Interventions

water with glucose DIETARY_SUPPLEMENT

0.75 g/kg body weight of glucose added to water

glucose beverage; glucose beverage (60 min)

water and whey protein DIETARY_SUPPLEMENT

0.75 g/kg body weight of whey protein added to water

whey protein beverage; whey protein beverage (60 min)

water with noncaloric sweetener DIETARY_SUPPLEMENT

0.15 g of sucralose added to water

noncaloric beverage; noncaloric beverage (60 min)

Eligibility Criteria

• Age: 9 Years - 14 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)

You may qualify if:

• children with no emotional, behavioral or learning problems

You may not qualify if:

• underweight children
• children with emotional, behavioral or learning problems
• children who dislike foods in study

Sponsors & Collaborators

• University of Toronto: lead
• Canadian Institutes of Health Research (CIHR): collaborator

Study Sites (1)

Department of Nutritional Sciences

Toronto, Ontario, M5S 3E2, Canada

Location

MeSH Terms

Conditions

Obesity

Interventions

Water; Glucose; Whey Proteins

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Hydroxides; Alkalies; Inorganic Chemicals; Anions; Ions; Electrolytes; Oxides; Oxygen Compounds; Hexoses; Monosaccharides; Sugars; Carbohydrates; Milk Proteins; Animal Proteins, Dietary; Dietary Proteins; Proteins; Amino Acids, Peptides, and Proteins; Whey; Milk; Dairy Products; Food; Diet, Food, and Nutrition; Physiological Phenomena; Food and Beverages

Study Officials

• Harvey Anderson, PhD

  University of Toronto

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: PREVENTION
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: January 6, 2011
• First Posted: January 7, 2011
• Study Start: January 1, 2010
• Primary Completion: December 1, 2012
• Study Completion: February 1, 2013
• Last Updated: February 15, 2013

Record last verified: 2013-02

Locations

CA (1)