The Use of 2D and 3D Imaging Modalities and Its Influence on Diagnosis and Treatment Planning in Orthodontics

NCT01246830 | Completed

• 1 other identifier: S52731
• Study Type: observational
• Target: 32
• Locations: 1 country
• Sites: 2

Brief Summary

Research questions:

• To compare 2D versus 3D cephalometric analysis: treatment planning and therapeutic outcome.
• To determine the accuracy and diagnostic ability and usability of the 3D cephalometric analysis.
• To evaluate the diagnostic ability and usability of the panoramic image derived from cone beam CT data as compared to 2D panoramic images.
• To evaluate the value of the cone beam CT data in cephalometric analysing process for orthodontic and maxillofacial surgery treatment. Hypotheses:
• The availability of the 3D cephalometric analysis influences the orthodontic and maxillofacial treatment plan and decision, and might change the treatment outcome.
• Panoramic images derived from cone beam CT data may provide equal information for diagnosis as conventional panoramic images.
• Cone beam CT will be able to replace "classic orthodontic imaging" being more time and dose efficient and having a beneficial effect on treatment outcome.

Conditions

Orthodontics; Malocclusion; Impacted Tooth; Cephalometry; Cone-Beam Computed Tomography; Panoramic Radiography

Outcome Measures

Primary Outcomes (1)

• Cephalometric analysis

  linear and angular cephalometric measurement

  at treatment planning step and after 2 years of treatment

Secondary Outcomes (1)

• outcome of orthodontic treatment

  after 2 years of treatment

Study Arms (2)

3D cephalometric analysis

Radiation: Cone-beam computed tomography (CBCT)

2D cephalometric analysis

Radiation: Panoramic radiograph, Cephalometric radiograph

Interventions

Panoramic radiograph, Cephalometric radiograph RADIATION

2D images that are used for orthodontic treatment planning

2D cephalometric analysis

Cone-beam computed tomography (CBCT) RADIATION

CBCT data will be used in 3D cephalometric analysis softwares

3D cephalometric analysis

Eligibility Criteria

• Age: 12 Years - 25 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Patients who are seeking orthodontic and maxillofacial surgery treatments at the University Hospital Leuven with the need of conventional panoramic radiographs, cephalometric radiographs and cone beam CT images.

You may qualify if:

• age 12-25 years old
• Patients with malocclusions
• Patients with jaw relation defect both with or without the need of orthognathic surgery
• Patients with maxillofacial defects: tumors and trauma
• Patients with eruption problems: embedded or impacted teeth which have to be removed

You may not qualify if:

• Patients with congenital deformities
• Patients with systemic diseases that may effect the growth formation: growth factor defect and thyroid hormone defect.

Sponsors & Collaborators

• Universitaire Ziekenhuizen KU Leuven: lead
• KU Leuven: collaborator

Study Sites (2)

Katholieke Universiteit Leuven

Leuven, 3000, Belgium

Location

University Hospital Leuven

Leuven, 3000, Belgium

Location

Related Publications (14)

• Broadbent BH. A new x-ray technique and its application to orthodontia. Angle Orthodontist 1931;51: 115-150

  BACKGROUND

• Swennen GR, Schutyser F, Barth EL, De Groeve P, De Mey A. A new method of 3-D cephalometry Part I: the anatomic Cartesian 3-D reference system. J Craniofac Surg. 2006 Mar;17(2):314-25. doi: 10.1097/00001665-200603000-00019.

  PMID: 16633181 BACKGROUND

• Swennen GR, Schutyser F. Three-dimensional cephalometry: spiral multi-slice vs cone-beam computed tomography. Am J Orthod Dentofacial Orthop. 2006 Sep;130(3):410-6. doi: 10.1016/j.ajodo.2005.11.035.

  PMID: 16979502 BACKGROUND

• Olszewski R, Cosnard G, Macq B, Mahy P, Reychler H. 3D CT-based cephalometric analysis: 3D cephalometric theoretical concept and software. Neuroradiology. 2006 Nov;48(11):853-62. doi: 10.1007/s00234-006-0140-x. Epub 2006 Sep 29.

  PMID: 17009024 BACKGROUND

• Scarfe WC, Farman AG. What is cone-beam CT and how does it work? Dent Clin North Am. 2008 Oct;52(4):707-30, v. doi: 10.1016/j.cden.2008.05.005.

  PMID: 18805225 BACKGROUND

• Carter L, Farman AG, Geist J, Scarfe WC, Angelopoulos C, Nair MK, Hildebolt CF, Tyndall D, Shrout M; American Academy of Oral and Maxillofacial Radiology. American Academy of Oral and Maxillofacial Radiology executive opinion statement on performing and interpreting diagnostic cone beam computed tomography. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 Oct;106(4):561-2. doi: 10.1016/j.tripleo.2008.07.007. No abstract available.

  PMID: 18928899 BACKGROUND

• Hassan B, van der Stelt P, Sanderink G. Accuracy of three-dimensional measurements obtained from cone beam computed tomography surface-rendered images for cephalometric analysis: influence of patient scanning position. Eur J Orthod. 2009 Apr;31(2):129-34. doi: 10.1093/ejo/cjn088. Epub 2008 Dec 23.

  PMID: 19106265 BACKGROUND

• Lou L, Lagravere MO, Compton S, Major PW, Flores-Mir C. Accuracy of measurements and reliability of landmark identification with computed tomography (CT) techniques in the maxillofacial area: a systematic review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Sep;104(3):402-11. doi: 10.1016/j.tripleo.2006.07.015. Epub 2006 Oct 27.

  PMID: 17709072 BACKGROUND

• de Oliveira AE, Cevidanes LH, Phillips C, Motta A, Burke B, Tyndall D. Observer reliability of three-dimensional cephalometric landmark identification on cone-beam computerized tomography. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009 Feb;107(2):256-65. doi: 10.1016/j.tripleo.2008.05.039. Epub 2008 Aug 20.

  PMID: 18718796 BACKGROUND

• Periago DR, Scarfe WC, Moshiri M, Scheetz JP, Silveira AM, Farman AG. Linear accuracy and reliability of cone beam CT derived 3-dimensional images constructed using an orthodontic volumetric rendering program. Angle Orthod. 2008 May;78(3):387-95. doi: 10.2319/122106-52.1.

  PMID: 18416632 BACKGROUND

• Brown AA, Scarfe WC, Scheetz JP, Silveira AM, Farman AG. Linear accuracy of cone beam CT derived 3D images. Angle Orthod. 2009 Jan;79(1):150-7. doi: 10.2319/122407-599.1.

  PMID: 19123719 BACKGROUND

• Olszewski R, Tanesy O, Cosnard G, Zech F, Reychler H. Reproducibility of osseous landmarks used for computed tomography based three-dimensional cephalometric analyses. J Craniomaxillofac Surg. 2010 Apr;38(3):214-21. doi: 10.1016/j.jcms.2009.05.005. Epub 2009 Jul 1.

  PMID: 19574058 BACKGROUND

• Proffit WR, Fields HW Jr., Sarver DM. Contemporary Orthodontics. 4th ed, Mosby Inc., Elsevier Science, Philadelphia, 2006.

  BACKGROUND

• White SC, Pharoah MJ. The evolution and application of dental maxillofacial imaging modalities. Dent Clin North Am. 2008 Oct;52(4):689-705, v. doi: 10.1016/j.cden.2008.05.006.

  PMID: 18805224 BACKGROUND

MeSH Terms

Conditions

Malocclusion; Tooth, Impacted

Interventions

Radiography, Panoramic

Condition Hierarchy (Ancestors)

Tooth Diseases; Stomatognathic Diseases

Intervention Hierarchy (Ancestors)

Radiography, Dental; Radiography; Diagnostic Imaging; Diagnostic Techniques and Procedures; Diagnosis; Diagnosis, Oral; Dentistry

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 22, 2010
• First Posted: November 23, 2010
• Study Start: January 1, 2012
• Primary Completion: December 1, 2013
• Study Completion: September 1, 2014
• Last Updated: December 3, 2014

Record last verified: 2010-09

Locations

BE (2)