NCT01244256

Brief Summary

The objective of this trial is to evaluate the comparative efficacy of the combination of Clotrimazole + Gentamicin + Beclomethasone in study subjects with a condition of contaminated dermatosis showing bilateral symmetrical lesions.

Trial Health

33
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Trial recruitment is currently suspended
Enrollment
80

participants targeted

Target at P50-P75 for phase_2

Timeline
Completed

Started Apr 2007

Shorter than P25 for phase_2

Geographic Reach
1 country

1 active site

Status
suspended

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2007

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2007

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2007

Completed
3.1 years until next milestone

First Submitted

Initial submission to the registry

October 22, 2010

Completed
28 days until next milestone

First Posted

Study publicly available on registry

November 19, 2010

Completed
Last Updated

November 3, 2022

Status Verified

November 1, 2022

Enrollment Period

4 months

First QC Date

October 22, 2010

Last Update Submit

November 1, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Efficacy of the treatment in patient with infected dermatoses

    21 days of treatment

Secondary Outcomes (1)

  • evaluate the safety and tolerability of both formulations in the course of treatmen

    21 days of treatment

Study Arms (2)

Treatment with Clotrimazole + Gentamicin + Beclomethasone

EXPERIMENTAL
Drug: Clotrimazole + Gentamicin + Beclomethasone

Treatment with Clotrimazole + Gentamicin

ACTIVE COMPARATOR
Drug: Clotrimazole + Gentamicin

Interventions

Treatment with Clotrimazole + Gentamicin + Beclomethasone

Treatment with Clotrimazole + Gentamicin + Beclomethasone

Treatment with Clotrimazole + Gentamicin

Treatment with Clotrimazole + Gentamicin

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Subject search of both sexes, regardless of color or social class
  • From age to 18, with good mental health
  • Carriers of two outbreaks of acne contaminated
  • Subjects who agree to return follow-up visits
  • Research subjects who agree to participate and sign the Deed of Consent

You may not qualify if:

  • Subject Research carriers of susceptibility to gentamicin
  • Research subjects suffering from sensitivity to clotrimazole
  • Research subjects suffering from sensitivity to beclomethasone
  • Research subjects who are making use of steroids or steroidal anti-inflammatory and non-steroidal drugs or who made use of topical or oral 15 days ago
  • Research subjects who are doing immunosuppressive treatment
  • Research subjects with a diagnosis of eosinophilic folliculitis or Pseudo-folliculitis barbae and groin
  • Pregnant and lactating

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

LAL Clinica

Valinhos, São Paulo, 13276245, Brazil

Location

MeSH Terms

Conditions

Folliculitis

Interventions

ClotrimazoleGentamicinsBeclomethasone

Condition Hierarchy (Ancestors)

Hair DiseasesSkin DiseasesSkin and Connective Tissue Diseases

Intervention Hierarchy (Ancestors)

ImidazolesAzolesHeterocyclic Compounds, 1-RingHeterocyclic CompoundsAminoglycosidesGlycosidesCarbohydratesPregnadienetriolsPregnadienesPregnanesSteroidsFused-Ring CompoundsPolycyclic CompoundsSteroids, Chlorinated

Study Officials

  • Alexandre Frederico, médico

    Azidus Brasil

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
INDUSTRY
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator Dr. Alexandre Frederico

Study Record Dates

First Submitted

October 22, 2010

First Posted

November 19, 2010

Study Start

April 1, 2007

Primary Completion

August 1, 2007

Study Completion

September 1, 2007

Last Updated

November 3, 2022

Record last verified: 2022-11

Locations