NCT01243905

Brief Summary

The purpose of this study is to examine the effectiveness of group psychoeducation for the psychological distress of mothers with the children of high-functioning pervasive developmental disorder and for their behavior based on disorder traits.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
74

participants targeted

Target at P50-P75 for phase_2

Timeline
Completed

Started Sep 2010

Shorter than P25 for phase_2

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2010

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

November 8, 2010

Completed
11 days until next milestone

First Posted

Study publicly available on registry

November 19, 2010

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2011

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2012

Completed
Last Updated

January 19, 2011

Status Verified

January 1, 2011

Enrollment Period

1.2 years

First QC Date

November 8, 2010

Last Update Submit

January 18, 2011

Conditions

Outcome Measures

Primary Outcomes (1)

  • Change from baseline in the total score of the General Health Questionaire 28(GHQ28) at 21 weeks

    GHQ:It is the shorten version of the General Health Questionaire 60. It consists four categories;somatic symptoms,anxiety and insomnia,social dysfunction and depressive tendency.

    Baseline, 21 weeks

Secondary Outcomes (2)

  • Change from baseline in the total score of the General Health Questionaire 28(GHQ28) at 7 weeks

    the baseline, 7weeks, 21weeks

  • Change from baseline in the total score of the Abnormal Behavior Checklist at 7 weeks

    the baseline, 7weeks, 21weeks

Study Arms (2)

Family psychoeducation plus TAU

ACTIVE COMPARATOR

Family psychoeducational therapy in addition to treatment as usual for the child (TAU)

Other: Family psychoeducational therapy plus TAU

Treatment as usual

PLACEBO COMPARATOR

Treatment as usual for the child (TAU)

Other: Treatment as usual

Interventions

Group psychoeducation every two weeks for eight weeks in addition to treatment as usual administered by physicians

Family psychoeducation plus TAU

Treatment as usual administered by physicians

Treatment as usual

Eligibility Criteria

Sexfemale
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Mothers whose children have been diagnosed with any disorders by DSM-Ⅳ-TR as: 1) Autistic disorder and not mental retardation; 2) Asperger disorder; or 3) Pervasive developmental disorder not otherwise specified and not mental retardation
  • Children were diagnosed at more than 3 months before allocation
  • Children were between 2 and 6.5 years and have more than 6 months as pre-school period at allocation
  • Mothers who are native speakers of Japanese.
  • Mothers who are biological mother of and actually bringing their children.

You may not qualify if:

  • Mothers who are at risk of taking an emotional toll and unable to understand the contents of psychoeducation for any reason.
  • Mothers who are not allowed to participate in this study judged by the doctors of the children for any reason.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Nagoya City University Hospital

Nagoya, Aichi-ken, 467-8601, Japan

RECRUITING

Nagoya City University Hospital

Nagoya, Aichi-ken, Japan

RECRUITING

MeSH Terms

Conditions

Child Development Disorders, Pervasive

Interventions

Therapeutics

Condition Hierarchy (Ancestors)

Neurodevelopmental DisordersMental Disorders

Study Officials

  • Masako Suzuki, MD

    Nagoya City University Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

November 8, 2010

First Posted

November 19, 2010

Study Start

September 1, 2010

Primary Completion

December 1, 2011

Study Completion

March 1, 2012

Last Updated

January 19, 2011

Record last verified: 2011-01

Locations