NCT01210209

Brief Summary

RATIONALE: Studying samples of blood in the laboratory from patients with cancer and their relatives may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: This research study is looking at blood samples collected from patients with Ewing sarcoma and their relatives.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
350

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2010

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 7, 2010

Completed
9 months until next milestone

First Submitted

Initial submission to the registry

September 25, 2010

Completed
3 days until next milestone

First Posted

Study publicly available on registry

September 28, 2010

Completed
8.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2019

Completed
Last Updated

May 19, 2021

Status Verified

May 1, 2021

Enrollment Period

9.5 years

First QC Date

September 25, 2010

Last Update Submit

May 18, 2021

Conditions

Sarcoma

Keywords

Ewing sarcomaEwing sarcoma/peripheral primitive neuroectodermal tumor (PNET)

Outcome Measures

Primary Outcomes (1)

  • Identification and characterization of susceptibility genes in patients with Ewing sarcoma

    Identification and characterization of susceptibility genes in patients with Ewing sarcoma

    Through study completion, an average of 10 years

Interventions

genome-wide association studyOTHER

Eligibility Criteria

Age0 Years - 120 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with Ewing's sarcoma, with idenfication of a specific translocation of Ewing's sarcoma

DISEASE CHARACTERISTICS: * Patients with Ewing sarcoma * Relatives of Ewing sarcoma patients PATIENT CHARACTERISTICS: * Patients with a fusion genes specific of Ewing Sarcoma PRIOR CONCURRENT THERAPY: * Not applicable

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Study Sites (1)

Institut Curie Hopital

Paris, 75005, France

Location

Related Links

MeSH Terms

Conditions

SarcomaSarcoma, EwingNeuroectodermal Tumors, Primitive, Peripheral

Interventions

Genome-Wide Association Study

Condition Hierarchy (Ancestors)

Neoplasms, Connective and Soft TissueNeoplasms by Histologic TypeNeoplasmsOsteosarcomaNeoplasms, Bone TissueNeoplasms, Connective TissueNeuroectodermal Tumors, PrimitiveNeoplasms, NeuroepithelialNeuroectodermal TumorsNeoplasms, Germ Cell and EmbryonalNeoplasms, Glandular and EpithelialNeoplasms, Nerve Tissue

Intervention Hierarchy (Ancestors)

Epidemiologic Research DesignEpidemiologic MethodsInvestigative TechniquesMolecular EpidemiologyGenetic Association StudiesGenetic TechniquesOligonucleotide Array Sequence AnalysisSequence AnalysisPublic HealthEnvironment and Public Health

Study Officials

  • Olivier Delattre, MD

    Institut Curie

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
FAMILY BASED
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 25, 2010

First Posted

September 28, 2010

Study Start

January 7, 2010

Primary Completion

July 1, 2019

Study Completion

July 1, 2019

Last Updated

May 19, 2021

Record last verified: 2021-05

Locations

FR(1)