Modelling of Energy Expenditure From Heart Rate, Accelerometry and Other Physiological Parameters
Modelheart
Modelling of 24h Energy Expenditure From Heart Rate, Actimetry and Other Parameters Recorded Under Free-living Conditions
2 other identifiers
interventional
120
1 country
1
Brief Summary
At this time, 24h energy expenditure is rarely assessed under free-living conditions for specific individuals because of the lack of cheap and accurate software/materials to record the energy expenditure. Some affordable and convenient tools (Polar heart rate monitor, Actiheart, SenseWear Armband) are available on the market but the predictive equations comprised into the software provided with these tools generally miscalculate the energy expenditure (by about +/-10%). Because of this deficiency, the investigators have a poor knowledge of the modification of the energy expended during daily life activities and over 24h in subjects belonging to groups of various ages and physiological states. The investigators hypothesise that it could be possible to improve the energy expenditure prediction. The project aims at providing a mathematical model (equations) that predicts energy expenditure with an error near to 5%. Two groups of 60 sedentary to athletic normal weight volunteers aged between 18-60 years participate to this study. The first group stay for 26h in calorimetric chambers. During this stay energy expenditure ,heart rate, accelerometry, and other parameters are recorded during various activities. These data will serve to construct the model. The same type of recordings are performed on second group of volunteers in free living conditions. Their energy expenditure is measured overall by doubly labeled water. The data of the second group will serve to validate the model. The error percentage of the model is defined by the ratio of the value of the difference between prediction and reference measure to the reference measure. Concordance between predictions and measures will be evaluated by Bland - Altman plots.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Jan 2009
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2009
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 1, 2009
CompletedStudy Completion
Last participant's last visit for all outcomes
September 1, 2010
CompletedFirst Submitted
Initial submission to the registry
September 24, 2010
CompletedFirst Posted
Study publicly available on registry
September 27, 2010
CompletedOctober 6, 2025
September 1, 2010
10 months
September 24, 2010
October 1, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
energy expenditure
indirect calorimetry
one point recorded each minute for 26 hours
Secondary Outcomes (5)
energy expenditure
one point at the end of the 10-day period
heart rate
one point recorded each minute for 26 hours or 10 days
Accelerometry
one point by minute for 26 hours or 10 days
hunger and emotional state perception
evaluation before and after each meal
hedonic evaluation of 6 food products
before and after each meal
Study Arms (2)
calorimetric chamber
EXPERIMENTALFree living conditions
EXPERIMENTALInterventions
Participants stayed 26h in a calorimetric chamber. They performed a series of physical activities such as walking on a treadmill at different speeds, writing, standing, standing-sitting, stepper , rest , sleeping and eating. They also performed a power test on an ergocycle at different speeds.
Volunteers followed the protocol of doubly labeled water to evaluate their energy expenditure during 10 days in free living conditions. For this period, their heart rate, parameters of actimetry and other parameters were recorded.
Eligibility Criteria
You may qualify if:
- men and women
- age: 18-60 years
- BMI between 19 and 25 kg/m²
- subject considered as healthy after clinical examination and medical questionnaire
- subject giving his/her written informed consent
- subject willing to comply with study procedures
- affiliated to National Health Insurance
You may not qualify if:
- biological results judged abnormal by investigator
- positive serologies to HIV or HCV
- respiratory failure or cardiovascular problem
- taking medicine : beta blockers, corticoids, anti-inflammatory drug, thyroid hormones, insulin
- abnormal ECG
- more than 10% of weight or gain loss in the three last months
- tumoral, inflammatory, pulmonary, renal, digestive or liver diseases
- surgery made less than 6 months before the study beginning
- thyroid disease
- pregnant women and nursing mother
- insanity
- smoker
- claustrophobic
- no affiliated to national health insurance people
- refusal to sign informed consent
- +2 more criteria
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Centre de Recherche en Nutrition Humaine d'Auvergne
Clermont-Ferrand, Auvergne, 63009, France
Related Links
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Yves Boirie, MD-PhD
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
September 24, 2010
First Posted
September 27, 2010
Study Start
January 1, 2009
Primary Completion
November 1, 2009
Study Completion
September 1, 2010
Last Updated
October 6, 2025
Record last verified: 2010-09