NCT01201655

Brief Summary

The purpose of this study is to investigate the impact of splenectomy coupled with portal-azygous disconnection on hepatocarcinogenesis in patients with post-hepatitic cirrhosis after hepatitis B or C virus infection by retrospective case-control study,We hope to find a new idear and method to prevent or cure HCC.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
5,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2010

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2010

Completed
9 months until next milestone

First Submitted

Initial submission to the registry

September 13, 2010

Completed
1 day until next milestone

First Posted

Study publicly available on registry

September 14, 2010

Completed
2.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2012

Completed
Last Updated

September 14, 2010

Status Verified

January 1, 2010

Enrollment Period

2.9 years

First QC Date

September 13, 2010

Last Update Submit

September 13, 2010

Conditions

Liver CirrhosisCarcinoma, HepatocellularSplenomegalyLaparotomy

Keywords

Posthepatitic cirrhosis;Hepatocarcinogenesis;Splenectomy;

Eligibility Criteria

Age20 Years - 90 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

post-hepatitic cirrhosis with portal hypertension and hypersplenism patients

You may qualify if:

  • after surgery

You may not qualify if:

  • without surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Chen yong

Xi'an, Shaanxi, 710032, China

RECRUITING

MeSH Terms

Conditions

Liver CirrhosisCarcinoma, HepatocellularSplenomegaly

Condition Hierarchy (Ancestors)

Liver DiseasesDigestive System DiseasesFibrosisPathologic ProcessesPathological Conditions, Signs and SymptomsAdenocarcinomaCarcinomaNeoplasms, Glandular and EpithelialNeoplasms by Histologic TypeNeoplasmsLiver NeoplasmsDigestive System NeoplasmsNeoplasms by SiteHypertrophyPathological Conditions, Anatomical

Study Officials

  • Chen yong, professor

    Xia jielai

    STUDY DIRECTOR

Central Study Contacts

Chen yong, professor

CONTACT

13891915509cheny@fmmu.edu.cn

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

September 13, 2010

First Posted

September 14, 2010

Study Start

January 1, 2010

Primary Completion

December 1, 2012

Study Completion

December 1, 2012

Last Updated

September 14, 2010

Record last verified: 2010-01

Locations

CN(1)