Key Insights

Highlights

Success Rate

82% trial completion

Published Results

58 trials with published results (20%)

Research Maturity

148 completed trials (51% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

11.4%

33 terminated out of 289 trials

Success Rate

81.8%

-4.7% vs benchmark

Late-Stage Pipeline

17%

50 trials in Phase 3/4

Results Transparency

39%

58 of 148 completed with results

Key Signals

58 with results82% success33 terminated

Data Visualizations

Phase Distribution

230Total
Not Applicable (58)
Early P 1 (2)
P 1 (46)
P 2 (74)
P 3 (40)
P 4 (10)

Trial Status

Completed148
Unknown62
Terminated33
Recruiting19
Withdrawn11
Active Not Recruiting8

Trial Success Rate

81.8%

Benchmark: 86.5%

Based on 148 completed trials

Clinical Trials (289)

Showing 20 of 20 trials
NCT07298577Not ApplicableEnrolling By Invitation

Use of Gender, Age, Alfa-fetoprotein (AFP), and Des-gamma-carboxyprothrombin (PIVKA-II) or GAAD Score in Addition to Ultrasound for Surveillance of People At-risk for Developing Hepatocellular Carcinoma in Asia in Order to Detect Early Liver Cancer

NCT02366286Completed

Hepatitis B and Hepatitis C as Risk Factors for Hepatocellular Carcinoma in African and Asian Immigrants

NCT04246177Phase 3CompletedPrimary

Safety and Efficacy of Lenvatinib (E7080/MK-7902) With Pembrolizumab (MK-3475) in Combination With Transarterial Chemoembolization (TACE) in Participants With Incurable/Non-metastatic Hepatocellular Carcinoma (MK-7902-012/E7080-G000-318/LEAP-012)

NCT05486572Not ApplicableRecruitingPrimary

Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI

NCT07227012Phase 1RecruitingPrimary

Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.

NCT05461430Completed

Mass Response of Tumor Cells as a Biomarker for Rapid Therapy Guidance (TraveraRTGx)

NCT04180072Not ApplicableActive Not RecruitingPrimary

Atezolizumab Plus Bevacizumab With HCC and HBV Infection

NCT03727633Phase 2TerminatedPrimary

Hepatocellular Carcinoma on Cirrhosis With Child A/B7 and Hepatic Intra Arterial Injection of Idarubicin/Lipiodol Emulsion

NCT06687941Phase 1Recruiting

A Study to Evaluate the Tolerability, Safety, and PK of AST-201 in Patients With GPC3-positive Advanced Solid Tumors

NCT04008797Phase 1Active Not Recruiting

A Study of E7386 in Combination With Other Anticancer Drug(s) in Participants With Solid Tumor

NCT04102098Phase 3Active Not RecruitingPrimary

A Study of Atezolizumab Plus Bevacizumab Versus Active Surveillance as Adjuvant Therapy in Patients With Hepatocellular Carcinoma at High Risk of Recurrence After Surgical Resection or Ablation

NCT07010497Phase 2RecruitingPrimary

A Prospective Study to Evaluate the Safety and Efficacy of the Combination Therapy of Irpagratinib, Atezolizumab, and Bevacizumab in Patients With Hepatocellular Carcinoma

NCT02439008Not ApplicableTerminatedPrimary

Early Biomarkers of Tumor Response in High Dose Hypofractionated Radiotherapy Word Package 3 : Immune Response

NCT04777851Phase 3TerminatedPrimary

Regorafenib-pembrolizumab vs. TACE/TARE in Intermediate Stage HCC Beyond Up-to-7

NCT03713593Phase 3CompletedPrimary

Safety and Efficacy of Lenvatinib (E7080/MK-7902) in Combination With Pembrolizumab (MK-3475) Versus Lenvatinib as First-line Therapy in Participants With Advanced Hepatocellular Carcinoma (MK-7902-002/E7080-G000-311/LEAP-002)

NCT02081755Phase 4Enrolling By InvitationPrimary

Safety and Efficacy of Everolimus Treatment in Liver Transplantation for Liver Cancer

NCT05366829Phase 2RecruitingPrimary

Tislelizumab Consolidation After Liver-Directed Therapy for Hepatocellular Carcinoma

NCT05337137Phase 1CompletedPrimary

A Study of Nivolumab and Relatlimab in Combination With Bevacizumab in Advanced Liver Cancer

NCT03894917RecruitingPrimary

Characterizing Disease Biology, Treatment and Toxicity in Older Adults With Hepatocellular Carcinoma

NCT05908786Phase 1CompletedPrimary

A Study Evaluating The Efficacy and Safety of Neoadjuvant Immunotherapy Combinations in Patients With Surgically Resectable Hepatocellular Carcinoma

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