Depression and Quality of Life in Chronic Heart Failure Patients and the Caregivers
1 other identifier
interventional
51
1 country
1
Brief Summary
Anxiety and depression are often present in patients with chronic heart failure (CHF). This study aimed to evaluate the influence of anxiety and depression on the physical function, disability, and quality of life (QOL) in CHF. This study examined the effects of 8-week home-based exercise on these parameters, and investigated the correlations between these outcome changes.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Dec 2006
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
December 1, 2006
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2007
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2007
CompletedFirst Submitted
Initial submission to the registry
September 7, 2010
CompletedFirst Posted
Study publicly available on registry
September 9, 2010
CompletedSeptember 9, 2010
September 1, 2010
1 year
September 7, 2010
September 7, 2010
Conditions
Keywords
Outcome Measures
Primary Outcomes (4)
Psychologic aspect
Anxiety and depression was measured by Hospital Anxiety and Depression Scale (HADS).
8 weeks
Functional capacity
Functional capacity was assessed by six-minute walk test (6MWT).
8 weeks
Disability level
Groningen Activity Restriction Scale (GARS)
8 weeks
Quality of life
Minnesota Living with Heart Failure Questionnaire (MHFQ) was used to assess quality of life.
8 weeks
Study Arms (1)
Exercise
EXPERIMENTALInterventions
Eligibility Criteria
You may qualify if:
- Clinical diagnosis of CHF for more than 6 months (NYHA Classes I-III)
- Medically stable for at least 3 months
You may not qualify if:
- Malignancy
- Psychiatric disease, primary neuromusculoskeletal or respiratory diseases that affected the assessment of functional or exercise capacity
- Changes in medication occurred during the study period
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
National Taiwan University Hospital
Taipei, 100, Taiwan
Related Publications (1)
Chien CL, Lee CM, Wu YW, Wu YT. Home-based exercise improves the quality of life and physical function but not the psychological status of people with chronic heart failure: a randomised trial. J Physiother. 2011;57(3):157-63. doi: 10.1016/S1836-9553(11)70036-4.
PMID: 21843830DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Ying-Tai Wu, Ph.D
National Taiwan University Hospital
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
September 7, 2010
First Posted
September 9, 2010
Study Start
December 1, 2006
Primary Completion
December 1, 2007
Study Completion
December 1, 2007
Last Updated
September 9, 2010
Record last verified: 2010-09