Tweens to Teens Project at Penn State
T2T@PSU
"Gender Development in Early Adolescence: Prenatal Hormones and Family Socialization"
2 other identifiers
observational
188
1 country
1
Brief Summary
The goal of this study is to help investigators to understand more about the development of characteristics related to being male or female (what is called gender development). The investigators will study girls with congenital adrenal hyperplasia (CAH) aged 10 to 13 to learn more about the girls' interests and activities, thoughts and feeling about being female, and family relationships. This will help investigators to understand the ways in which gender development is shaped by hormones and family relationships.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Aug 2009
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 1, 2009
CompletedFirst Submitted
Initial submission to the registry
August 2, 2010
CompletedFirst Posted
Study publicly available on registry
August 19, 2010
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 1, 2013
CompletedStudy Completion
Last participant's last visit for all outcomes
July 1, 2013
CompletedJanuary 8, 2018
January 1, 2018
3.9 years
August 2, 2010
January 4, 2018
Conditions
Keywords
Study Arms (2)
Girls
Girls with 21-hydroxylase deficiency (21-OHD) congenital adrenal hyperplasia (CAH) ages 10-13
Parents
Parent, guardian, or significant caretaker of girls with CAH
Interventions
Girls answer questions about activities and interests, school, feelings about being a girl, stage of physical development, and family relationships during a home interview , provide saliva samples, and participate in phone interviews to answer questions about daily activities .
Eligibility Criteria
We will study girls with the 21-hydroxylase deficiency (21-OHD) form of congenital adrenal hyperplasia (CAH) aged 10 to 13. Parents of participants are also included.
You may qualify if:
- Girls with classical or non-classical CAH due to 21-OHD
- Girls will be aged 10-13 years at initial recruitment
- Parents will include biological mothers and fathers as well as step-parents and/or other guardians/significant caregivers
- Parents/guardians may range in age from 18 years of age to 65 years of age.
You may not qualify if:
- Girls who are not within the age range of 10-13 years old at initial recruitment
- CAH not due to the 21-OHD form
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
The Pennsylvania State University, Dept. of Psychology - Tweens to Teens Project
University Park, Pennsylvania, 16802, United States
Biospecimen
Samples of saliva will be collected from participants with CAH for genetic testing (specific mutations of CYP21 gene) and to obtain hormone levels.
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Sheri A Berenbaum, PhD
The Pennsylvania State University
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor of Psychology and Pediatrics
Study Record Dates
First Submitted
August 2, 2010
First Posted
August 19, 2010
Study Start
August 1, 2009
Primary Completion
July 1, 2013
Study Completion
July 1, 2013
Last Updated
January 8, 2018
Record last verified: 2018-01