NCT01183325

Brief Summary

For small (2-3cm) ventral and umbilical hernias the discussion for primary suture repair or the use of mesh continues. About 5 years ago the Ventralex patch was introduced, which combines a layer of PTFE mesh with a small polypropylene mesh and includes a circular memory ring. Despite the elegance of using this patch, recent experience showed several drawbacks both in design and efficacy (3). With the recent development of the Proceed Ventral Patch (PVP), new elements have been introduced to overcome some of these issues. The aim of this study is to evaluate the efficacy of clinical placement of the PVP in the intra-abdominal position in the treatment of small ventral hernias.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
160

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Sep 2009

Longer than P75 for not_applicable

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2009

Completed
12 months until next milestone

First Submitted

Initial submission to the registry

August 12, 2010

Completed
5 days until next milestone

First Posted

Study publicly available on registry

August 17, 2010

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2011

Completed
2.4 years until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2013

Completed
Last Updated

December 5, 2014

Status Verified

December 1, 2014

Enrollment Period

1.6 years

First QC Date

August 12, 2010

Last Update Submit

December 4, 2014

Conditions

Keywords

Umbilical and small ventral hernias less than 3cm diameter

Outcome Measures

Primary Outcomes (1)

  • Percentage of adequately placed patches

    At T 0 days

Secondary Outcomes (7)

  • Perioperative morbidity rate

    Within 30 days

  • Pre- and postoperative pain

    At T 0 day, T 30 days and T 1 year

  • Number of patients needed a repositioning of the patch

    At T 0 days

  • Reasons for inadequate positioning

    At T 0 days

  • Number of repositioning necessary

    At T 0 days

  • +2 more secondary outcomes

Study Arms (1)

Proceed Ventral Patch placement

EXPERIMENTAL

Placement of a Proceed Ventral Patch for umbilical and small ventral hernias less than 3cm diameter with and without laparoscopic control

Device: Proceed Ventral Patch placement

Interventions

Placement of a Proceed Ventral Patch for umbilical and small ventral hernias less than 3cm diameter with and without laparoscopic control

Proceed Ventral Patch placement

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adult patient
  • Written informed consent
  • Umbilical, primary ventral hernias smaller than 3cm diameter

You may not qualify if:

  • Hernias larger than 3cm
  • Recurrence
  • Children
  • Emergency cases
  • Incisional hernias

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Imelda Hospital

Bonheiden, Belgium

Location

University Hospital Ghent

Ghent, 9000, Belgium

Location

Related Links

MeSH Terms

Conditions

Hernia, UmbilicalHernia, Ventral

Condition Hierarchy (Ancestors)

Infant, Newborn, DiseasesCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesHernia, AbdominalHerniaPathological Conditions, AnatomicalPathological Conditions, Signs and Symptoms

Study Officials

  • Frederik Berrevoet, MD

    University Hospital, Ghent

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 12, 2010

First Posted

August 17, 2010

Study Start

September 1, 2009

Primary Completion

April 1, 2011

Study Completion

September 1, 2013

Last Updated

December 5, 2014

Record last verified: 2014-12

Locations