FASEP
FASEP Fabry and Stroke Epidemiological Protocol RISK FACTORS IN ISCHEMIC STROKE PATIENTS WITH FABRY DISEASE AN INTERNATIONAL, MULTICENTER, EPIDEMIOLOGICAL PROTOCOL
Sponsor study identifier
observational
1,000
2 countries
14
Study Start
September 2010
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
April 2012
Actual (reported)Study Completion
April 2012
Actual (reported)More than one million people in Europe suffer from a stroke every day. Normally older people have a stroke, but also a significant number of younger people between 18 and 55 years. Usually, these can only be explained for a minority by the classical risk factors such as diabetes, overweight and high blood pressure. New studies indicate that in about 1 - 2 % of the younger stroke patients the etiology can be an undiagnosed genetic disease, e.g. Fabry disease. Fabry disease is a lysosomal storage disorder known to cause vasculopathy. The purpose of this study is to determine in a large number of young stroke patients, how many strokes were caused by Fabry disease and what risk factors might be able to predict this disease.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
April 2012
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
August 16, 2010
Actual (reported)August 17, 2010
Actual (reported)September 2010
Date type not reportedThis date has not been verified as actual or estimated.
April 2012
Actual (reported)April 2012
Actual (reported)all adult patients (18 - 60 years of age) with an acute cerebrovascular event of any etiology
Adult patients with acute ischemic cerebrovascular event of any ischemic etiology
Department of Neurology, Kreiskrankenhaus Altenburg
Altenburg, 04600, Germany
Dept. of Neurology, Vivantes Netzwerk für Gesundheit GmbH, Klinikum Neukölln
Berlin, 12351, Germany
Department of Neurology, Allgemeines Krankenhaus Celle
Celle, 29223, Germany
Department of Neurology, Klinikum Chemnitz gGmbH
Chemnitz, 09131, Germany
Heinrich-Heine University Duesseldorf, Dept. of Neurology
Düsseldorf, D-40225, Germany
Universitätsklinikum Giessen, Department of Neurology
Giessen, 35392, Germany
Department of Neurology S10, Universitaetsklinikum Hamburg-Eppendorf
Fabry diagnostic will be done centrally: blood samples will be stored for analysis of a-galactosidase in blood, Gb3 as well as lyso-Gb3. In all cases direct analysis of the gene will be done, especially in females where due to the Lyonisation effect a-galactosidase activity might be normal in blood although the patient might suffer from Fabry disease.
Arndt Rolfs, MD
University of Rostock, Albrecht-Kossel-Institute for Neuroregeneration
1,000 participants (actual enrollment reported by the registry).
First Submitted
August 16, 2010
First Posted
August 17, 2010
Study Start
September 2010
Date type not reportedThis date has not been verified as actual or estimated.
Inflammation and Post-Stroke Depression
Contact the study team to confirm eligibility.
Hamburg, 20246, Germany
Universität Heidelberg, Klinik für Neurologie
Heidelberg, 69120, Germany
Department of Neurology, Universitaetsklinikum Jena
Jena, 07740, Germany
Dept. of Neurology, Ökumenisches Hainich Klinikum gGmbH
Mühlhausen / Thürigen, 99974, Germany
Universitätsklinikum Regensburg, Klinik für Neurologie
Regensburg, 93053, Germany
University of Rostock, Department of Neurology
Rostock, D-18055, Germany
University of Ulm, Department of Neurology
Ulm, D-89081, Germany
Institute of Psychiatry and Neurology, Dept. of Neurology
Warsaw, 02-957, Poland
Primary Completion
April 2012
Actual (reported)Study Completion
April 2012
Actual (reported)Last Updated
June 14, 2012
Record last verified: 2012-06
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: