Stroke Ready - Optimizing Acute Stroke Care

NCT03645590 | Completed Results

• 1 other identifier: U01MD010579
• Study Type: interventional
• Target: 5,970
• Locations: 1 country
• Sites: 1

Brief Summary

The study aims to increase acute stroke treatment rates in Flint, Michigan through a two-pronged approach of hospital and community level interventions. It also aims to inform future stroke preparedness interventions by exploring the relative importance of hospital optimization and community interventions.

Conditions

Stroke, Acute; Stroke

Outcome Measures

Primary Outcomes (1)

• Utilization of Thrombolysis Among Ischemic Stroke and Transient Ischemic Attack (TIA) Patients

  Proportion of Tissue Plasminogen Activator (tPA) treatment utilization among ischemic stroke and TIA patients in pre vs. post intervention periods in all Genesee county hospitals. This is a distinct group of county-wide patients who may or may not include any individuals who received the workshop intervention.

  Data for this outcome was from county-wide medical records from July 2010 through September 2017 (pre-intervention) and from October 2017 through March 2020 (post-intervention, defined by initiation of the emergency department optimization component).

Secondary Outcomes (1)

• Percent of Stroke and TIA Patients Who Arrive to the Emergency Department by Ambulance

  Data was gathered retrospectively from the medical record for Flint stroke or TIA patients from October 2017 through March 2020, following initiation of the Stroke Ready intervention.

Study Arms (1)

Stroke Ready Community intervention

EXPERIMENTAL

We divided the Flint community into four quadrants. We will focus our workshops and posters on one quadrant, but not exclusively, moving quadrants every 6 months over the course of two years.

Behavioral: Stroke Ready

Interventions

Stroke Ready BEHAVIORAL

Stroke Ready community intervention consists of peer facilitated educational workshops, stroke music video, and mass media campaign including print materials (e.g. posters, brochure), health promotion mailers, radio/Television public health service announcements, and the Stroke Ready website and Facebook page.

Stroke Ready Community intervention

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

Sponsors & Collaborators

• University of Michigan: lead
• National Institute on Minority Health and Health Disparities (NIMHD): collaborator

Study Sites (1)

Flint Community

Flint, Michigan, 48502, United States

Location

Related Publications (2)

• Robles MC, Springer MV, Corches CL, Burke JF, Lin CC, Oliver A, Skolarus LE. Stroke Ready Very Brief Intervention Improves Immediate Postintervention Stroke Preparedness. Circ Cardiovasc Qual Outcomes. 2020 Dec;13(12):e006643. doi: 10.1161/CIRCOUTCOMES.120.006643. Epub 2020 Nov 26. No abstract available.

  PMID: 33238728 DERIVED

• Skolarus LE, Sales AE, Zimmerman MA, Corches CL, Landis-Lewis Z, Robles MC, McBride AC, Rehman N, Oliver A, Islam N, Springer MV, O'Brien A, Bailey S, Morgenstern LB, Meurer WJ, Burke JF. Stroke Ready: a multi-level program that combines implementation science and community-based participatory research approaches to increase acute stroke treatment: protocol for a stepped wedge trial. Implement Sci. 2019 Mar 7;14(1):24. doi: 10.1186/s13012-019-0869-3.

  PMID: 30845958 DERIVED

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Results Point of Contact

• Title: Principal Investigator
• Organization: University of Michigan

lerusche@umich.edu

734-615-2766

Study Officials

• Lesli Skolarus, MD

  University of Michigan

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: No
• Restrictive Agreement: No

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor of Neurology

Model Details: Stroke Ready is a pre-post design. Outcome measures are pre-intervention and post-intervention assessments of thrombolytic utilization among stroke and TIA patients (not workshop participants) across the entire city of Flint, Michigan.

Study Record Dates

• First Submitted: March 23, 2017
• First Posted: August 24, 2018
• Study Start: June 20, 2018
• Primary Completion: March 31, 2021
• Study Completion: March 31, 2021
• Last Updated: May 1, 2026
• Results First Posted: May 1, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)