NCT01182064

Brief Summary

Patients with a cardiac stab wound could be complicated by a posttraumatic acute myocardial infarction (PAMI). Traditionally, the investigators can explain it by the occlusion of a coronary artery; but the PAMI isn´t constantly related with coronary artery injuries or their damage in the cardiac injury repair. The investigators objectives are to know the PAMI incidence, make an approximation to PAMI pathophysiology, and propose management strategies.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
51

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Apr 2007

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2007

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2008

Completed
2.4 years until next milestone

First Submitted

Initial submission to the registry

August 13, 2010

Completed
3 days until next milestone

First Posted

Study publicly available on registry

August 16, 2010

Completed
Last Updated

August 16, 2010

Status Verified

March 1, 2007

First QC Date

August 13, 2010

Last Update Submit

August 13, 2010

Conditions

Myocardial Infarction

Keywords

Heart injuriesPosttraumatic myocardial infarctionEchocardiographyCoronary angiography

Outcome Measures

Primary Outcomes (1)

  • Posttraumatic acute myocardial infarct

    2 days

Secondary Outcomes (1)

  • Posttraumatic acute myocardial infarct without coronary injury

    10 days

Study Arms (3)

Non infarct

Posttraumatic acute myocardial infarct without coronary injury

Posttraumatic acute myocardial infarct with coronary injury

Eligibility Criteria

Age14 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

The study included patients admitted to the emergency department of the San Vicente de Paul University Hospital with a penetrating stab cardiac injury without previous injuries

You may qualify if:

  • Heart stab Injury

You may not qualify if:

  • Previous cardiac injuries, coronary artery disease with previous diagnostic, previous coronary angiography (for any indication)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

San Vicente de Paul Hospital

Medellín, Antioquia, Colombia

Location

Related Publications (1)

  • Castano W, Morales CH, Senior JM, Benjumea WY, Sanchez J. Relationship of echocardiographic and coronary angiographic findings in patients with acute myocardial infarction secondary to penetrating cardiac trauma. J Trauma Acute Care Surg. 2012 Jul;73(1):111-6. doi: 10.1097/TA.0b013e318256a0d8.

    PMID: 22743380DERIVED

MeSH Terms

Conditions

Myocardial InfarctionHeart Injuries

Condition Hierarchy (Ancestors)

Myocardial IschemiaHeart DiseasesCardiovascular DiseasesVascular DiseasesInfarctionIschemiaPathologic ProcessesPathological Conditions, Signs and SymptomsNecrosisThoracic InjuriesWounds and Injuries

Study Officials

  • Carlos H Morales, MD, MSc

    Antioquia University

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

August 13, 2010

First Posted

August 16, 2010

Study Start

April 1, 2007

Study Completion

April 1, 2008

Last Updated

August 16, 2010

Record last verified: 2007-03

Locations

CO(1)