Cognitive Remediation and Functional Skills Training in Schizophrenia
Specificity and Generalizability of Cognitive Remediation and Functional Skills Training in Schizophrenia
1 other identifier
interventional
75
1 country
1
Brief Summary
This randomized trial is examining whether a treatment called cognitive remediation is more effective when it is paired with a social and functional skills training component.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for early_phase_1 schizophrenia
Started Jul 2007
Typical duration for early_phase_1 schizophrenia
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
July 1, 2007
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 1, 2010
CompletedFirst Submitted
Initial submission to the registry
August 3, 2010
CompletedFirst Posted
Study publicly available on registry
August 5, 2010
CompletedStudy Completion
Last participant's last visit for all outcomes
September 1, 2010
CompletedNovember 17, 2016
August 1, 2010
3.1 years
August 3, 2010
November 16, 2016
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
neurocognition
12 weeks
Secondary Outcomes (5)
functional competence
12 weeks
neurocognition
24 weeks
neurocognition
36 weeks
functional competence
24 weeks
functional competence
36 weeks
Study Arms (3)
Cognitive remediation
EXPERIMENTALCognitive remediation
Functional Adaptive Skills Training
ACTIVE COMPARATORFunctional and social skills group treatment
Combined Treatment
ACTIVE COMPARATORCombined cognitive remediation and functional adaptive skills training
Interventions
Computer-based, therapist-lead cognitive remediation
Functional adaptive skills training. Group treatment to foster the acquisition of social and adaptive skills
Eligibility Criteria
You may qualify if:
- Diagnosis of schizophrenia or schizoaffective disorder
- Enrolled in outpatient mental health care
- Reading level of 6th grade or higher
- English speaking
You may not qualify if:
- Medical conditions known to affect cognition
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Queen's University
Kingston, Ontario, K7L 3N6, Canada
Related Publications (1)
Bowie CR, McGurk SR, Mausbach B, Patterson TL, Harvey PD. Combined cognitive remediation and functional skills training for schizophrenia: effects on cognition, functional competence, and real-world behavior. Am J Psychiatry. 2012 Jul;169(7):710-8. doi: 10.1176/appi.ajp.2012.11091337.
PMID: 22581070DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Christopher R Bowie, PhD
Queen's University
Study Design
- Study Type
- interventional
- Phase
- early phase 1
- Allocation
- RANDOMIZED
- Masking
- TRIPLE
- Who Masked
- PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor
Study Record Dates
First Submitted
August 3, 2010
First Posted
August 5, 2010
Study Start
July 1, 2007
Primary Completion
August 1, 2010
Study Completion
September 1, 2010
Last Updated
November 17, 2016
Record last verified: 2010-08
Data Sharing
- IPD Sharing
- Will not share