Impact of Information Prescriptions on Medication Adherence in Emergency Department (ED) Patients

NCT01174706 | Completed

• 2 other identifiers: NA_000382091RC1LM010424-01
• Study Type: interventional
• Target: 3,940
• Locations: 1 country
• Sites: 3

Brief Summary

The main objectives of this research are:

1. 1.To identify factors that influence medication adherence rates in Emergency Department (ED) patients.
2. 2.To measure the effects of alternative information prescriptions on medication adherence rates of ED patients.
3. 3.To measure the effects of alternative information prescriptions (IRxs) on health and service utilization.

Conditions

Patient Compliance; Medication Adherence; Medication Non-Adherence

Keywords

infections; flu; abdominal pain; chest pain; cold; fever; different acute care conditions

Outcome Measures

Primary Outcomes (1)

• Medication adherence

  Self-reported medication adherence.For subjects discharged with a prescription medication or an over the counter (OTC) medication with a specified dosage and frequency, medication adherence will be measured by the number of doses taken divided by the number of doses specified.

  one week after index ED visit

Secondary Outcomes (1)

• Filling of prescription medicine

  within one week of index ED visit

Study Arms (4)

Usual care arm

EXPERIMENTAL

Patients randomized to this group will receive usual care. Usual care at the three study sites varies but will be defined as whatever information is usually given to patients regarding the prescription medication or over the counter medicine they were prescribed at emergency department discharge.

Behavioral: Information prescriptions

Information prescription

EXPERIMENTAL

Patients randomized to this arm will receive written information from Medline Plus regarding the prescription or over the counter medicine they have been prescribed at ED discharge plus information on their health condition.

Behavioral: Information prescriptions

Informationist

EXPERIMENTAL

Patients in this arm will receive the same information as patients in group 2 but will also be given contact information for a clinical informationist if they have further questions about their prescription medicine or over the counter medicine prescribed at ED discharge.

Behavioral: Information prescriptions

practical assistance

EXPERIMENTAL

Subjects will be offered practical assistance with obtaining prescription such as location of most convenient pharmacy and hours of operation, programs that offer drugs more cheaply, fax prescription from ED to pharmacy

Behavioral: Information prescriptions

Interventions

Information prescriptions BEHAVIORAL

One arm will receive usual care at discharge. The other three arms will receive practical assistance and/or an information prescription which will consist of written information from Medline Plus and access to a clinical informationist if subject has additional information needs.

Information prescription; Informationist; Usual care arm; practical assistance

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

Sponsors & Collaborators

• Johns Hopkins University: lead
• National Library of Medicine (NLM): collaborator

Study Sites (3)

Johns Hopkins Hospital

Baltimore, Maryland, 21201, United States

Location

Johns Hopkins Bayview Medical Center

Baltimore, Maryland, 21224, United States

Location

Howard County General Hospital

Columbia, Maryland, 21044, United States

Location

Related Publications (1)

• McCarthy ML, Ding R, Roderer NK, Steinwachs DM, Ortmann MJ, Pham JC, Bessman ES, Kelen GD, Atha W, Retezar R, Bessman SC, Zeger SL. Does providing prescription information or services improve medication adherence among patients discharged from the emergency department? A randomized controlled trial. Ann Emerg Med. 2013 Sep;62(3):212-23.e1. doi: 10.1016/j.annemergmed.2013.02.002. Epub 2013 Apr 3.

  PMID: 23561463 RESULT

MeSH Terms

Conditions

Patient Compliance; Medication Adherence; Infections; Influenza, Human; Abdominal Pain; Chest Pain; Common Cold; Fever

Condition Hierarchy (Ancestors)

Patient Acceptance of Health Care; Treatment Adherence and Compliance; Health Behavior; Behavior; Respiratory Tract Infections; Orthomyxoviridae Infections; RNA Virus Infections; Virus Diseases; Respiratory Tract Diseases; Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Signs and Symptoms, Digestive; Picornaviridae Infections; Body Temperature Changes

Study Officials

• Melissa L McCarthy, ScD

  Associate Professor

  PRINCIPAL INVESTIGATOR

• Nancy Roderer, MLS

  Professor and Director of the Welch Medical Library

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: INVESTIGATOR
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 3, 2010
• First Posted: August 4, 2010
• Study Start: November 1, 2010
• Primary Completion: September 1, 2011
• Study Completion: December 1, 2011
• Last Updated: August 21, 2018

Record last verified: 2018-08

Locations

US (3)