Systems of Support Study for Childhood Depression
SOS
Evaluation of Family Focused Treatment for Childhood Depression
3 other identifiers
interventional
134
1 country
2
Brief Summary
This study is designed to compare two treatments for depression in pre-adolescent (7-13 year old) children. A family-focused treatment will be compared to an individual child-focused treatment in this 14-week intervention.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable depression
Started Jan 2010
Longer than P75 for not_applicable depression
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2010
CompletedFirst Submitted
Initial submission to the registry
July 7, 2010
CompletedFirst Posted
Study publicly available on registry
July 9, 2010
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 1, 2015
CompletedStudy Completion
Last participant's last visit for all outcomes
December 31, 2016
CompletedJanuary 24, 2018
January 1, 2018
5.3 years
July 7, 2010
January 22, 2018
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Adequate Depression Treatment Response
50% improvement on Children's Depression Rating Scale-Revised
3 months
Secondary Outcomes (2)
Interviewer-rated Depression Severity
3 Months
Children's Self-Report of Depression Symptoms
3 Months
Study Arms (2)
Family Focused Treatment (FFT)
EXPERIMENTAL15 session family-based treatment emphasizing improving relationship skills to combat depression symptoms and support recovery.
Individual Treatment (IP)
ACTIVE COMPARATOR15 session individually-based treatment to assist children in understanding the causes of their symptoms.
Interventions
FFT is designed to specifically address the developmental needs of school-aged children and their parents through an emphasis on fostering positive and supportive parent-child interactions that scaffold the development of a positive self, to help parents provide the child additional positive feedback on his/her developmentally appropriate achievements, and to enhance family and child coping. This treatment is conducted with the child and his/her parent(s) and includes education about depression, communication training, relationship enhancement, and problem-solving.
The goals of the treatment are to foster the therapeutic relationship, to provide a supportive and empathic setting where the child can come to better understand his/her emotions/feelings and address issues underlying current symptoms. Therapeutic goals will be addressed through reflection and clarification of feelings/emotions and understanding the child's perception of the context of depressed feelings.
Eligibility Criteria
You may qualify if:
- current Depressive Disorder
- ages 7-13 years
- living with at least one biological parent willing to participate
You may not qualify if:
- thought disturbance
- severe conduct disorders
- unstable on antidepressant medications
- continuation in current non-study treatment
- non-English speaking
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (2)
UCLA Semel Institute for Neuroscience and Human Behavior
Los Angeles, California, 90095, United States
Boston University
Boston, Massachusetts, 02215, United States
Related Publications (5)
Tompson MC, Pierre CB, Haber FM, Fogler JM, Groff AR, Asarnow JR. Family-focused treatment for childhood-onset depressive disorders: results of an open trial. Clin Child Psychol Psychiatry. 2007 Jul;12(3):403-20. doi: 10.1177/1359104507078474.
PMID: 17953128BACKGROUNDTompson MC, Boger KD, Asarnow JR. Enhancing the developmental appropriateness of treatment for depression in youth: integrating the family in treatment. Child Adolesc Psychiatr Clin N Am. 2012 Apr;21(2):345-84. doi: 10.1016/j.chc.2012.01.003. Epub 2012 Mar 17.
PMID: 22537731RESULTTompson MC, Sugar CA, Langer DA, Asarnow JR. A Randomized Clinical Trial Comparing Family-Focused Treatment and Individual Supportive Therapy for Depression in Childhood and Early Adolescence. J Am Acad Child Adolesc Psychiatry. 2017 Jun;56(6):515-523. doi: 10.1016/j.jaac.2017.03.018. Epub 2017 Apr 7.
PMID: 28545757RESULTTompson MC, Langer DA, Hughes JL, Asarnow JR. Family-Focused Treatment for Childhood Depression: Model and Case Illustrations. Cogn Behav Pract. 2017 Aug;24(3):269-287. doi: 10.1016/j.cbpra.2016.06.003.
PMID: 28966545RESULTAsarnow JR, Tompson MC, Klomhaus AM, Babeva K, Langer DA, Sugar CA. Randomized controlled trial of family-focused treatment for child depression compared to individual psychotherapy: one-year outcomes. J Child Psychol Psychiatry. 2020 Jun;61(6):662-671. doi: 10.1111/jcpp.13162. Epub 2019 Dec 15.
PMID: 31840263DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate Professor
Study Record Dates
First Submitted
July 7, 2010
First Posted
July 9, 2010
Study Start
January 1, 2010
Primary Completion
May 1, 2015
Study Completion
December 31, 2016
Last Updated
January 24, 2018
Record last verified: 2018-01