Clinical Implication of DAC (Detrusor After-contraction)
DAC
A New Approach to Clinical Implication of Detrusor After-contraction (DAC)
2 other identifiers
observational
2,309
1 country
1
Brief Summary
The aims of this study are
- to confirm whether detrusor after-contraction (DAC) is a true contraction or not with a new approach
- and to understand clinical implication of DAC
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2007
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2007
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2008
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2008
CompletedFirst Submitted
Initial submission to the registry
June 29, 2010
CompletedFirst Posted
Study publicly available on registry
July 1, 2010
CompletedJuly 1, 2010
June 1, 2010
1.9 years
June 29, 2010
June 30, 2010
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
to confirm whether DAC is a true contraction or not
no change of Pdet when patients cough could confirm that DAC was a true contraction. Because an artifact occurred when a catheter was pressed against bladder wall or urethra, no change of intravesical pressure and increase of abdominal pressure finally induced a negative deflection of Pdet and this change of Pdet could be regarded as an artifact.
up to 2 years (2007.Jan-2008.Dec)
Secondary Outcomes (1)
Past medical history including neurological disorders and pelvic irradiation were also included in the database
up to 2 years (2007.Jan-2008.Dec)
Study Arms (1)
DAC group
patients who show detrusor after-contraction during voiding cystometrography (CMG)
Eligibility Criteria
2,309 patients more than 18 years old with neurogenic or non-neurogenic voiding dysfunction who performed urodynamic studies
You may qualify if:
- Indications and selection of patients for conduction of urodynamic studies (UDS) were followed as the recommendation of ICS (international continence society).
You may not qualify if:
- Patients with indwelling catheters, urinary tract infection and urinary stones were excluded from this study
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Seoul National University Hospital
Seoul, Seoul, 110-744, South Korea
Related Publications (1)
Ruarte AC, Podesta ML, Medel R. Detrusor after-contractions in children with normal urinary tracts. BJU Int. 2002 Aug;90(3):286-93. doi: 10.1046/j.1464-410x.2002.02827.x.
PMID: 12133067BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Seung-June Oh, M.D.,Ph.D.
Seoul National University Hospital
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
June 29, 2010
First Posted
July 1, 2010
Study Start
January 1, 2007
Primary Completion
December 1, 2008
Study Completion
December 1, 2008
Last Updated
July 1, 2010
Record last verified: 2010-06