The CLOQS Trial - Countdown Lights to Optimize Quality in Stroke

NCT01148602 | Completed

• 1 other identifier: UTSP Innovation
• Study Type: interventional
• Target: 3,452
• Locations: 1 country
• Sites: 3

Brief Summary

To reduce door-to-needle times in acute stroke treatment. Using an organizational behaviour intervention (a large stopwatch), we will post a visual cue to remind all parties that "time is brain". We hypothesize that this simple visual cue will improve door-to-CT scan times and door-to-needle treatment times, and thus improve treatment response, and reduce adverse events.

Conditions

Acute Stroke

Keywords

Acute stroke; Emergency departments; Quality Improvement; Improved Processes; tPA; door-to-needle; door-to-treatment

Outcome Measures

Primary Outcomes (1)

• Improved door-to-CT and door-to-needle times.

  Improved door-to-CT scan times and door-to-needle treatment times with tPA, with potentially improved response to treatment and reduction in adverse events.

  18 months

Study Arms (2)

'Off Clock'

NO INTERVENTION

Stopwatch timers will NOT be used for "off clock" weeks, so patients presenting with hyperacute stroke will be managed normally without the visual timer.

'On Clock"

ACTIVE COMPARATOR

LED stopwatch-clock timers will be posted for all patients presenting during "ON clock" weeks. All patients presenting with hyperacute stroke will be managed normally with the addition of a visual stopwatch timer.

Other: LED stopwatch-clock timers

Interventions

LED stopwatch-clock timers OTHER

We will attach a large, "in-your-face" red LED stopwatch-clock timers to the patient's stretcher at the moment of ED arrival to act as a constant visual reminder to all team members (physicians, RN's, CT technologists) of the urgency of the situation.

Also known as: Clocks, CLOQS, Clock, LED countdown timer

'On Clock"

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• All patients who present to the emergency room with acute stroke for consideration of treatment with tPA.

You may not qualify if:

• Patients presenting to the emergency room (door time) more than 4.5 hours after symptom onset

Sponsors & Collaborators

• Sunnybrook Health Sciences Centre: lead
• University Health Network, Toronto: collaborator
• Unity Health Toronto: collaborator

Study Sites (3)

Sunnybrook Health Sciences Centre

Toronto, Ontario, M4n 3M5, Canada

Location

St. Michael's Hospital

Toronto, Ontario, Canada

Location

University Health Network - Toronto Western Hospital

Toronto, Ontario, Canada

Location

MeSH Terms

Conditions

Stroke; Emergencies

Interventions

E1A-Associated p300 Protein

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

p300-CBP Transcription Factors; Histone Acetyltransferases; Lysine Acetyltransferases; Acetyltransferases; Acyltransferases; Transferases; Enzymes; Enzymes and Coenzymes; Transcription Factors; Proteins; Amino Acids, Peptides, and Proteins

Study Officials

• Richard Swartz, MD

  University of Toronto Stroke Program

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Dr.

Study Record Dates

• First Submitted: June 17, 2010
• First Posted: June 22, 2010
• Study Start: June 1, 2010
• Primary Completion: April 1, 2012
• Study Completion: April 1, 2012
• Last Updated: December 9, 2015

Record last verified: 2015-12

Locations

CA (3)