NCT01144884

Brief Summary

The annual incidence of neck pain has been reported to be 14.6%. Other studies outline a wide disparity in the lifetime incidence of neck pain ranging from 22% to 70%. Numerous treatment options exist for the management of neck pain however, there is limited evidence to support which interventions are most effective. Exercise based interventions are commonly used in the treatment of patients with neck pain however; it is not clear which patients are most likely to benefit from this type of treatment. The purpose of this project is to develop a clinical prediction rule (CPR) to identify which patients with neck pain have a greater probability of benefiting from a standardized program of education and exercise. Ninety (90) patients referred to physical therapy will undergo a standardized examination to assess potential predictor variables. Upon completion of the examination a standardized treatment program of education and exercise will be administered regardless of examination findings. Self report measures will be administered on the initial examination and on follow up visits at 2, 4, and 6 weeks. A questionnaire and outcome measures will be also mailed out 6 months after initiation of treatment to assess long-term change. Once the treatment plan is completed, patients will be classified as having either a successful or non-successful response. Subjects which rated their perceived recovery on the Global Rating of Chance (GROC) as "a very great deal better", "a great deal better", "quite a bit better", or "moderately better" (i.e., a score of +4 or greater) will be categorized as having a successful outcome. The primary endpoints to determine the outcome will be analyzed at 6 weeks and 6 months. The result of this study will assist physical therapists to identify sub-groups of patients likely to benefit from a program of education and exercise. The categorization of patients in groups based on beneficial treatments may help to provide improved outcomes.

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
91

participants targeted

Target at P50-P75 for not_applicable

Geographic Reach
1 country

9 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2009

Completed
10 months until next milestone

First Submitted

Initial submission to the registry

June 9, 2010

Completed
7 days until next milestone

First Posted

Study publicly available on registry

June 16, 2010

Completed
2.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2012

Completed
Last Updated

May 20, 2014

Status Verified

May 1, 2014

Enrollment Period

3.3 years

First QC Date

June 9, 2010

Last Update Submit

May 19, 2014

Conditions

Keywords

Neck paineducationexerciseclinical prediction rule

Outcome Measures

Primary Outcomes (4)

  • Perceived Disability as measured by the Neck Disability Index

    6 weeks

  • Perceived pain intensity as measure by the Numeric pain rating scale

    Baseline, 2 weeks, 4 weeks, 6 weeks, 6 months

  • Perceived fear avoidance beliefs as measure by the Fear Avoidance Belief Questionnaire

    6 weeks

  • Perceived rating of change as measure by the Global Rating of Change

    6 weeks

Secondary Outcomes (4)

  • Disability as measured by the Neck Disability Index

    baseline, 2 weeks, 4 weeks, 6 months

  • Perceived pain intensity as measure by the Numeric pain rating scale

    baseline, 2 weeks, 4 weeks, 6 months

  • Perceived fear avoidance beliefs as measure by the Fear Avoidance Belief Questionnaire

    baseline, 2 weeks, 4 weeks, 6 months

  • Perceived rating of change as measure by the Global Rating of Change

    2 weeks, 4 weeks, 6 months

Study Arms (1)

Single arm trial

OTHER

Education:To standardize, treatment education will consist of counsel to stay active. Details will be given to subjects verbally \& reinforced in the home booklet. Posture:Facilitation of proper posture has been show to increase recruitment of the lumbar multifidus \& deep neck flexors. Instruction will be given verbally \& in writing. Stretching:Stretching exercises will be targeted to address these common impairments. Patients will be introduced to proper stretching procedures. Each stretch will be held for 30s \& repeated two times,each side as applicable. The following stretches will be performed: Upper trap Anterior/medial Scalene Suboccipital Pectoralis Muscular Performance: Muscle performance will be trained incorporating components of strength, endurance and motor control. Each of the exercises listed below are outlined based on progressions. Isometric Cervical Extension Craniocervical flexion Seated Row Seated "T" Palms Up Seated Side Arm Raises

Other: Procedure (education and exercise)

Interventions

education/exercise

Single arm trial

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Over the age of 18
  • Primary complaint of neck pain with or without unilateral UE symptoms
  • Neck Disability Index (NDI) of 10% or greater.

You may not qualify if:

  • Presence of medical "red flags' noted in the Neck Medical Screening Questionnaire. (i.e. tumor, fracture, etc.)
  • Evidence of central nervous system (CNS) involvement (i.e. hyperreflexia, sensory disturbances in the hand, intrinsic muscle wasting of the hands, unsteadiness during walking, nystagmus, loss of visual acuity, impaired sensation of the face, altered taste, the presence of pathological reflexes such as Hoffman's or Babinski reflexes, etc.)
  • Spasmodic torticollis
  • Frequent migraine
  • Fibromyalgia
  • Prior Surgery to the neck or thoracic spine
  • Severe psychiatric illness
  • Inability to comply with treatment and follow-up schedule
  • Pending legal action regarding their neck pain
  • Insufficient English language skills to complete all questionnaires.
  • Latex allergies

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (9)

Florida Hospital Sports Medicine & Rehabilitation - Altamonte

Altamonte Springs, Florida, 32701, United States

Location

Brooks Rehabilitation - Monument

Jacksonville, Florida, 32225, United States

Location

Brooks Rehabilitation -Spine Center

Jacksonville, Florida, 32225, United States

Location

Florida Hospital Sports Medicine & Rehabilitation - Kissimmee

Kissimmee, Florida, 34741, United States

Location

Brooks Rehabilitation - Lake Mary

Lake Mary, Florida, 32746, United States

Location

Brooks Rehabilitation - Flemming Island

Orange Park, Florida, 32003, United States

Location

Florida Hospital Sports Medicine & Rehabilitation - RDV

Orlando, Florida, 32810, United States

Location

Brooks Rehabilitation - Waterford

Orlando, Florida, 32828, United States

Location

Florida Hospital Sports Medicine & Rehabilitation - Oviedo

Oviedo, Florida, 32765, United States

Location

MeSH Terms

Conditions

Neck PainMotor Activity

Interventions

Educational StatusExercise

Condition Hierarchy (Ancestors)

PainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsBehavior

Intervention Hierarchy (Ancestors)

Socioeconomic FactorsPopulation CharacteristicsMotor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • William Hanney, PT DPT

    University of Central Florida

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

June 9, 2010

First Posted

June 16, 2010

Study Start

August 1, 2009

Primary Completion

December 1, 2012

Last Updated

May 20, 2014

Record last verified: 2014-05

Locations