Mothers With a History of Depression and Their 10-14 Year Old Daughters
The Neural Correlates of Mood and Cognitive Bias in a Population at Risk for Depression: Maternal Cognitive and Emotional Functioning
2 other identifiers
observational
240
1 country
2
Brief Summary
The purpose of this study is to investigate risk factors associated with depression and how such factors might be transmitted cross-generationally. The investigators are conducting an integrative assessment of emotion regulation and stress reactivity in a group of mothers with and without a history of depression and their daughters.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Feb 2004
Longer than P75 for all trials
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2004
CompletedFirst Submitted
Initial submission to the registry
May 21, 2010
CompletedFirst Posted
Study publicly available on registry
May 25, 2010
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2011
CompletedStudy Completion
Last participant's last visit for all outcomes
April 1, 2011
CompletedJune 23, 2011
June 1, 2011
7.2 years
May 21, 2010
June 21, 2011
Conditions
Outcome Measures
Primary Outcomes (1)
Onset of depression
participants are interviewed in an 18-month follow-up session
18 months
Study Arms (1)
children at risk for depression
children at familial risk for depression
Interventions
Eligibility Criteria
Eligible mothers must read and speak English fluently and have a child between the ages of 9 and 15 years old. Mothers must either have no history of psychopathology or have a history of depression during their child's lifetime.
You may qualify if:
- Eligible mothers must read and speak English fluently and have a child between the ages of 9 and 15 years old.
- Mothers must either have no history of psychopathology or have a history of depression during their child's lifetime.
You may not qualify if:
- Eligible mothers cannot:
- currently be in treatment for drug or alcohol abuse
- have significant symptomatology related to psychopathology outside of depression
- have a medical history of neurological injury or impairment.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Stanford Universitylead
- National Institute of Mental Health (NIMH)collaborator
Study Sites (2)
Stanford University Department of Psychology
Stanford, California, 94305, United States
Stanford University School of Medicine
Stanford, California, 94305, United States
Biospecimen
All participants are asked to submit saliva samples during their second session using sterile salivette containers in order to assess cortisol levels. There is no risk involved in giving these samples.
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Ian H Gotlib, PhD
Stanford University Department of Psychology
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
May 21, 2010
First Posted
May 25, 2010
Study Start
February 1, 2004
Primary Completion
April 1, 2011
Study Completion
April 1, 2011
Last Updated
June 23, 2011
Record last verified: 2011-06