NCT01127711

Brief Summary

The Cohort of Swedish Men began in 1997, when all men born between 1918 and 1952 and residing in two counties in central Sweden received a questionnaire including about 350 items concerning diet and other lifestyle factors. A second questionnaire was sent out in 2008-09.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
48,850

participants targeted

Target at P75+ for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 1997

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 1997

Completed
12.5 years until next milestone

First Submitted

Initial submission to the registry

May 20, 2010

Completed
1 day until next milestone

First Posted

Study publicly available on registry

May 21, 2010

Completed
Last Updated

February 28, 2014

Status Verified

February 1, 2014

Enrollment Period

3 months

First QC Date

May 20, 2010

Last Update Submit

February 27, 2014

Conditions

CancersCardiovascular DiseasesCataractGastrointestinal DiseasesOsteoporosisFractures

Outcome Measures

Primary Outcomes (10)

  • Prostate cancer

    1997-2010

  • Pancreatic cancer

    1997-2010

  • Stomach cancer

    1997-2010

  • Cataract

    1997-2010

  • LUTS (Lower urinary tract symptom)

    1997-2010

  • Cardiovascular Diseases

    1997-2010

  • Mortality

    1997-2010

  • Colorectal Cancer

    1997-2010

  • Bladder cancer

    1997-2010

  • Fractures, hip fractures

    1997-2014

Eligibility Criteria

Age45 Years - 79 Years
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Men born between 1918 and 1952, living in central Sweden (Örebro and Västmanlands counties)

You may qualify if:

  • All men born between 1918 and 1952, living in central Sweden

You may not qualify if:

  • None

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (11)

  • Larsson SC, Drca N, Bjorck M, Back M, Wolk A. Nut consumption and incidence of seven cardiovascular diseases. Heart. 2018 Oct;104(19):1615-1620. doi: 10.1136/heartjnl-2017-312819. Epub 2018 Apr 16.

    PMID: 29661934DERIVED

  • Larsson SC, Wallin A, Hakansson N, Stackelberg O, Back M, Wolk A. Type 1 and type 2 diabetes mellitus and incidence of seven cardiovascular diseases. Int J Cardiol. 2018 Jul 1;262:66-70. doi: 10.1016/j.ijcard.2018.03.099. Epub 2018 Mar 24.

    PMID: 29605469DERIVED

  • Larsson SC, Wolk A. Potato consumption and risk of cardiovascular disease: 2 prospective cohort studies. Am J Clin Nutr. 2016 Nov;104(5):1245-1252. doi: 10.3945/ajcn.116.142422. Epub 2016 Sep 28.

    PMID: 27680993DERIVED

  • Bellavia A, Stilling F, Wolk A. High red meat intake and all-cause cardiovascular and cancer mortality: is the risk modified by fruit and vegetable intake? Am J Clin Nutr. 2016 Oct;104(4):1137-1143. doi: 10.3945/ajcn.116.135335. Epub 2016 Aug 24.

    PMID: 27557655DERIVED

  • Xu H, Akesson A, Orsini N, Hakansson N, Wolk A, Carrero JJ. Modest U-Shaped Association between Dietary Acid Load and Risk of All-Cause and Cardiovascular Mortality in Adults. J Nutr. 2016 Aug;146(8):1580-5. doi: 10.3945/jn.116.231019. Epub 2016 Jul 6.

    PMID: 27385761DERIVED

  • Larsson SC, Tektonidis TG, Gigante B, Akesson A, Wolk A. Healthy Lifestyle and Risk of Heart Failure: Results From 2 Prospective Cohort Studies. Circ Heart Fail. 2016 Apr;9(4):e002855. doi: 10.1161/CIRCHEARTFAILURE.115.002855.

    PMID: 27072861DERIVED

  • Larsson SC, Wallin A, Wolk A. Dietary Approaches to Stop Hypertension Diet and Incidence of Stroke: Results From 2 Prospective Cohorts. Stroke. 2016 Apr;47(4):986-90. doi: 10.1161/STROKEAHA.116.012675. Epub 2016 Feb 11.

    PMID: 26869384DERIVED

  • Oskarsson V, Orsini N, Sadr-Azodi O, Wolk A. Fish consumption and risk of non-gallstone-related acute pancreatitis: a prospective cohort study. Am J Clin Nutr. 2015 Jan;101(1):72-8. doi: 10.3945/ajcn.113.076174. Epub 2014 Nov 5.

    PMID: 25527752DERIVED

  • Bellavia A, Larsson SC, Bottai M, Wolk A, Orsini N. Differences in survival associated with processed and with nonprocessed red meat consumption. Am J Clin Nutr. 2014 Sep;100(3):924-9. doi: 10.3945/ajcn.114.086249. Epub 2014 Jul 16.

    PMID: 25030780DERIVED

  • Bellavia A, Larsson SC, Bottai M, Wolk A, Orsini N. Fruit and vegetable consumption and all-cause mortality: a dose-response analysis. Am J Clin Nutr. 2013 Aug;98(2):454-9. doi: 10.3945/ajcn.112.056119. Epub 2013 Jun 26.

    PMID: 23803880DERIVED

  • Larsson SC, Virtamo J, Wolk A. Red meat consumption and risk of stroke in Swedish men. Am J Clin Nutr. 2011 Aug;94(2):417-21. doi: 10.3945/ajcn.111.015115. Epub 2011 Jun 8.

    PMID: 21653800DERIVED

Related Links

Biospecimen

Retention: SAMPLES WITH DNA

Saliva Blood

MeSH Terms

Conditions

NeoplasmsCardiovascular DiseasesCataractGastrointestinal DiseasesOsteoporosisFractures, Bone

Condition Hierarchy (Ancestors)

Lens DiseasesEye DiseasesDigestive System DiseasesBone Diseases, MetabolicBone DiseasesMusculoskeletal DiseasesMetabolic DiseasesNutritional and Metabolic DiseasesWounds and Injuries

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

May 20, 2010

First Posted

May 21, 2010

Study Start

September 1, 1997

Primary Completion

December 1, 1997

Last Updated

February 28, 2014

Record last verified: 2014-02