NCT01114685

Brief Summary

A comparison of changes in bone density following the same bone-health plan, but with a different bone-health supplement.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
354

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jun 2006

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2006

Completed
2.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2008

Completed
1.7 years until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2010

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

April 19, 2010

Completed
14 days until next milestone

First Posted

Study publicly available on registry

May 3, 2010

Completed
Last Updated

May 3, 2010

Status Verified

April 1, 2010

Enrollment Period

2.1 years

First QC Date

April 19, 2010

Last Update Submit

April 30, 2010

Conditions

Outcome Measures

Primary Outcomes (1)

  • Changes in Bone Mineral Density (BMD)

    Measurements of bone mineral density were conducted at baseline and 6 months from baseline in two different study groups following the same bone-health behavior modification plan, but with different versions of a bone-health calcium supplement.

    baseline and 6 months

Secondary Outcomes (1)

  • A comparison of changes from baseline in 43-blood chemistry panel and a self-reported quality of life inventory in both study groups

    six months

Study Arms (2)

Effects of taking AlgaeCal-1

ACTIVE COMPARATOR

Following a bone health plan with Algae-cal-1 supplement

Dietary Supplement: AlgaeCal-1

Effects of taking AlgaeCal-2

ACTIVE COMPARATOR

Following a bone-health plan while consuming AlgaeCal 2

Dietary Supplement: AlgaeCal-2

Interventions

AlgaeCal-1DIETARY_SUPPLEMENT

Daily consumption of 7 capsules containing bone health ingredients

Effects of taking AlgaeCal-1
AlgaeCal-2DIETARY_SUPPLEMENT

Taking 7 capsules a day for six months

Effects of taking AlgaeCal-2

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • All subjects were required to contact the physicians to ensure they had no medical issues that would preclude their participation.

You may not qualify if:

  • Younger the 18 years of age, and
  • Recommendations not to participate from their physicians.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Integrative Health Technologies

San Antonio, Texas, 78209, United States

Location

Related Publications (1)

  • Michalek JE, Preuss HG, Croft HA, Keith PL, Keith SC, Dapilmoto M, Perricone NV, Leckie RB, Kaats GR. Changes in total body bone mineral density following a common bone health plan with two versions of a unique bone health supplement: a comparative effectiveness research study. Nutr J. 2011 Apr 14;10:32. doi: 10.1186/1475-2891-10-32.

MeSH Terms

Conditions

Bone Diseases, Metabolic

Condition Hierarchy (Ancestors)

Bone DiseasesMusculoskeletal DiseasesMetabolic DiseasesNutritional and Metabolic Diseases

Study Officials

  • Gilbert R Kaats, PhD

    Integrative Health Technologies

    PRINCIPAL INVESTIGATOR
  • Harry G Preuss, MD

    Georgetown University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
NETWORK

Study Record Dates

First Submitted

April 19, 2010

First Posted

May 3, 2010

Study Start

June 1, 2006

Primary Completion

July 1, 2008

Study Completion

March 1, 2010

Last Updated

May 3, 2010

Record last verified: 2010-04

Locations