NCT01106339

Brief Summary

The purpose of this study is to define subgroups of patients with somatoform disorders due to DSM-IV by immunological, psychological and genetic characterization.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
52

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Aug 2007

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2007

Completed
2.7 years until next milestone

First Submitted

Initial submission to the registry

April 15, 2010

Completed
4 days until next milestone

First Posted

Study publicly available on registry

April 19, 2010

Completed
2.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2013

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2013

Completed
Last Updated

April 5, 2013

Status Verified

April 1, 2013

Enrollment Period

5.6 years

First QC Date

April 15, 2010

Last Update Submit

April 3, 2013

Conditions

Keywords

humanspatientssomatoform disordersfibromyalgiamyofascial pain syndrome diffusedepressionchronic fatigue syndromeinflammationinflammatory responsebiomarkerscytokinescell surface markersfunctional polymorphisms

Outcome Measures

Primary Outcomes (1)

  • Pattern of inflammatory biomarkers

    1 year

Secondary Outcomes (5)

  • Pattern of cell surface markers

    1 year

  • Functional polymorphisms

    1 year

  • Psychometric tests

    1 year

  • Demographic tests

    1 year

  • Severity of pain

    1 year

Study Arms (1)

A

Patients with somatoform disorders due to DSM-IV

Eligibility Criteria

Age18 Years - 90 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

chronic pain patients with a somatoform disorder due to DSM-IV

You may qualify if:

  • chronic pain patients with a somatoform disorder due to DSM-IV
  • chronic pain \> 6 months in several anatomical regions
  • presence of physical symptoms that suggest a general medical condition
  • the symptoms must cause clinically significant distress or impairment in social, occupational, or other areas of functioning
  • the physical symptoms are not under voluntary control
  • Psychic factors exclusively or in combination with a medical disease factor influence onset, severity, exacerbation or maintenance of symptoms decisively
  • fibromyalgia

You may not qualify if:

  • age \< 18 years
  • psychosis
  • symptoms fully explained by a general medical condition, by the direct effects of a substance, or by another mental disorder
  • pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Clinic of Anesthesiology, Dept. of Pain

Ulm, 89070, Germany

Location

Related Publications (1)

  • Schneider EM, Ma X, Stratz T, Muller W, Lorenz I, Seeling WD. Immunomodulatory function of the 5-HT3 receptor antagonist tropisetron. Scand J Rheumatol Suppl. 2004;119:34-40.

    PMID: 15515411BACKGROUND

Biospecimen

Retention: SAMPLES WITH DNA

Whole blood, serum, and white cells will be retained.

MeSH Terms

Conditions

Somatoform DisordersFibromyalgiaDepressionFatigue Syndrome, ChronicInflammation

Condition Hierarchy (Ancestors)

Mental DisordersMuscular DiseasesMusculoskeletal DiseasesRheumatic DiseasesNeuromuscular DiseasesNervous System DiseasesBehavioral SymptomsBehaviorEncephalomyelitisNeuroinflammatory DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Peter Steffen, MD

    Clinic of Anesthesiology, University Hospital Medical School, Steinhoevelstrasse 9, 89070 Ulm, Germany

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor, MD, MBA

Study Record Dates

First Submitted

April 15, 2010

First Posted

April 19, 2010

Study Start

August 1, 2007

Primary Completion

March 1, 2013

Study Completion

April 1, 2013

Last Updated

April 5, 2013

Record last verified: 2013-04

Locations