NCT00071162

Brief Summary

The Fibromyalgia Family Study identifies and collects blood samples from families with two or more members affected with Fibromyalgia Syndrome (FMS). The primary goal of the study is to identify genes that predispose people to FMS and/or symptoms related to FMS; identifying these genes may lead to a better understanding of the disease and more effective treatments.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
560

participants targeted

Target at P75+ for all trials

Geographic Reach
1 country

4 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 1999

Completed
4.1 years until next milestone

First Submitted

Initial submission to the registry

October 14, 2003

Completed
1 day until next milestone

First Posted

Study publicly available on registry

October 15, 2003

Completed
Last Updated

April 1, 2009

Status Verified

March 1, 2009

First QC Date

October 14, 2003

Last Update Submit

March 31, 2009

Conditions

FibromyalgiaIrritable Bowel SyndromeChronic Fatigue SyndromeDepression

Keywords

PainFatigueSleepDepressionIrritable Bowel SyndromeChronic Fatigue Syndrome

Eligibility Criteria

Age12 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

The population of this study is family based and aimed to recruit 160 multic-case FMS families. We plan to perform a genome scan and evaluate 200-300 linkage markers to FMS and FMS-related traits. Future plans include establishing a DNA and data repository for distribution for future studies.

You may qualify if:

  • Diagnosed with fibromyalgia according to the criteria of the American College of Rheumatology
  • Have at least one living family member who has also been diagnosed with fibromyalgia
  • No other major rheumatological disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (4)

University of Illinois at Peoria

Peoria, Illinois, 60612, United States

Location

University of Cincinnati

Cincinnati, Ohio, 45221, United States

Location

Case Western Reserve University

Cleveland, Ohio, 44109, United States

Location

University of Texas Health Sciences Center

San Antonio, Texas, 78229, United States

Location

Related Publications (1)

  • Yunus MB, Khan MA, Rawlings KK, Green JR, Olson JM, Shah S. Genetic linkage analysis of multicase families with fibromyalgia syndrome. J Rheumatol. 1999 Feb;26(2):408-12.

    PMID: 9972977BACKGROUND

Biospecimen

Retention: SAMPLES WITH DNA

DNA, whole blood

MeSH Terms

Conditions

FibromyalgiaIrritable Bowel SyndromeFatigue Syndrome, ChronicDepressionPainFatigue

Condition Hierarchy (Ancestors)

Muscular DiseasesMusculoskeletal DiseasesRheumatic DiseasesNeuromuscular DiseasesNervous System DiseasesColonic Diseases, FunctionalColonic DiseasesIntestinal DiseasesGastrointestinal DiseasesDigestive System DiseasesEncephalomyelitisNeuroinflammatory DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and SymptomsBehavioral SymptomsBehaviorNeurologic ManifestationsSigns and Symptoms

Study Officials

  • Sudha Iyengar, PhD

    Case Western Reserve University

    STUDY CHAIR

Study Design

Study Type
observational
Observational Model
FAMILY BASED
Time Perspective
RETROSPECTIVE
Sponsor Type
NIH

Study Record Dates

First Submitted

October 14, 2003

First Posted

October 15, 2003

Study Start

September 1, 1999

Last Updated

April 1, 2009

Record last verified: 2009-03

Locations

US(4)