Postoperative Cognitive Dysfunction After Total Knee or Hip Replacement Surgery in Fast-track Set-up
1 other identifier
observational
225
1 country
1
Brief Summary
The aim of this study is to quantify the incidence of postoperative cognitive dysfunction in the elderly patient (\>60y) after total hip or knee replacement surgery. The hypothesis is that the fast-track methodology with a mean hospital stay less than 3 days will help to minimize this reduction in memory and concentration.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Oct 2009
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 2009
CompletedFirst Submitted
Initial submission to the registry
April 13, 2010
CompletedFirst Posted
Study publicly available on registry
April 15, 2010
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 1, 2011
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2011
CompletedDecember 14, 2011
December 1, 2011
1.9 years
April 13, 2010
December 13, 2011
Conditions
Study Arms (1)
Surgery
This group (n=220) consist of patients undergoing hip or knee replacement in a fast-track setup and they are tested 3 times for postoperative cognitive dysfunction.
Interventions
Eligibility Criteria
patients undergoing fast-track knee or hip replacement surgery at one of the hospitals participating (Hidovre, Holstebro, Hørsholm, Århus)
You may qualify if:
- years of age or above
- ASA classification 1-4
- undergoing fast-track hip or knee replacement
You may not qualify if:
- anaesthesia within the past 90 days
- daily consumption of sleep or anxiety medication
- more than 35 units of alcohol per week
- lack of proper verbal and reading skills, Danish
- Serious hearing or visual impairment
- Mini mental status evaluation (MMSE) \< 24
- Parkinsons Disease or other neurological disease causing functional impairment
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Lene Krenklead
- Lundbeck Foundationcollaborator
Study Sites (1)
The Lundbeck Centre for fast-track hip/knee surgery
Copenhagen, Denmark
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Lene Krenk, Doctor
Rigshospitalet, Denmark
Study Design
- Study Type
- observational
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- MD
Study Record Dates
First Submitted
April 13, 2010
First Posted
April 15, 2010
Study Start
October 1, 2009
Primary Completion
September 1, 2011
Study Completion
December 1, 2011
Last Updated
December 14, 2011
Record last verified: 2011-12