Sponsor study identifier
Secondary identifiers
interventional
71
1 country
1
Study Start
March 2006
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
March 2008
Actual (reported)Study Completion
October 2008
Actual (reported)Systemic lupus erythematosus (SLE) is an independent risk factor for atherosclerosis. Endothelial dysfunction is the earliest marker of atherosclerosis and is measured by flow mediated dilation (FMD) of the brachial artery. The purpose of the study was to measure FMD in mild, stable SLE patients and look for change in FMD with the immunosuppressant drug mycophenolate mofetil (MMF).
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
October 2008
Actual (reported)Click on a node to explore related trials.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
March 2006
Date type not reportedThis date has not been verified as actual or estimated.
March 2008
Actual (reported)October 2008
Actual (reported)April 9, 2010
Actual (reported)April 12, 2010
Actual (reported)Flow mediated dilation
Measure of endothelial function using doppler ultrasound to measure brachial artery dilation in response to increase blood flow.
8 weeks
BILAG, SLEDAI,
8 weeks
Patients were given 1gm bd mycophenolate mofetil for 8 weeks
Arm 1 patients were given 1 gm bd mycophenolate mofetil for 8 weeks, The mycophenolate was dispensed as 500mg tablets.
Arm 2 patients were given 2 sugar pills bd for 8 weeks
Lupus Research Unit, St Thomas' Hospital
London, SE1 7EH, United Kingdom
David P D'Cruz, MD, FRCP
Guy's and St Thomas' NHS Foundation Trust
71 participants (actual enrollment reported by the registry).
First Submitted
April 9, 2010
First Posted
April 12, 2010
Study Start
March 2006
Date type not reportedThis date has not been verified as actual or estimated.
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Primary Completion
March 2008
Actual (reported)Study Completion
October 2008
Actual (reported)Last Updated
September 28, 2011
Record last verified: 2005-05
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Source: ClinicalTrials.gov.
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