Success Metrics

Clinical Success Rate
79.8%

Based on 305 completed trials

Completion Rate
80%(305/382)
Active Trials
67(13%)
Results Posted
70%(214 trials)
Terminated
77(15%)

Phase Distribution

Ph phase_4
72
14%
Ph not_applicable
38
7%
Ph phase_3
57
11%
Ph early_phase_1
6
1%
Ph phase_2
235
45%
Ph phase_1
104
20%

Phase Distribution

110

Early Stage

235

Mid Stage

129

Late Stage

Phase Distribution512 total trials
Early Phase 1First-in-human
6(1.2%)
Phase 1Safety & dosage
104(20.3%)
Phase 2Efficacy & side effects
235(45.9%)
Phase 3Large-scale testing
57(11.1%)
Phase 4Post-market surveillance
72(14.1%)
N/ANon-phased studies
38(7.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

74.6%

305 of 409 finished

Non-Completion Rate

25.4%

104 ended early

Currently Active

67

trials recruiting

Total Trials

525

all time

Status Distribution
Active(74)
Completed(305)
Terminated(104)
Other(42)

Detailed Status

Completed305
Terminated77
Recruiting43
unknown41
Withdrawn27
Active, not recruiting24

Development Timeline

Analytics

Development Status

Total Trials
525
Active
67
Success Rate
79.8%
Most Advanced
Phase 4

Trials by Phase

Early Phase 16 (1.2%)
Phase 1104 (20.3%)
Phase 2235 (45.9%)
Phase 357 (11.1%)
Phase 472 (14.1%)
N/A38 (7.4%)

Trials by Status

enrolling_by_invitation10%
unknown418%
withdrawn275%
not_yet_recruiting61%
completed30558%
active_not_recruiting245%
suspended10%
terminated7715%
recruiting438%

Recent Activity

Clinical Trials (525)

Showing 20 of 525 trialsScroll for more
NCT07524530Phase 2

Stem Cell Transplantation for Participants With Germline RUNX1 Associated Blood Cancers

Not Yet Recruiting
NCT03386539Phase 3

Tacrolimus/Everolimus vs. Tacrolimus/MMF in Pediatric Heart Transplant Recipients Using the MATE Score

Completed
NCT05457556Phase 3

Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome

Active Not Recruiting
NCT05327023Phase 1

Donor Lymphocyte Infusion After Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic Malignancies

Recruiting
NCT01729494Phase 4

Belatacept Early Steroid Withdrawal Trial

Completed
NCT03712878Phase 2

2-Step Approach to Stem Cell Transplant in Treating Participants With Hematological Malignancies

Completed
NCT06013423Phase 2

Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Diseases

Recruiting
NCT04370301Phase 2

Reduced Intensity Haploidentical Transplantation for the Treatment of Primary or Secondary Myelofibrosis

Recruiting
NCT04022239Phase 1

Bendamustine With or Without Cyclophosphamide in Preventing GVHD in Patients Undergoing Stem Cell Transplant

Recruiting
NCT03121001Phase 2

Study of HLA-Haploidentical Stem Cell Transplantation to Treat Clinically Aggressive Sickle Cell Disease

Recruiting
NCT07359859Phase 2

A Study of Ruxolitinib for Preventing Graft-Versus-Host Disease in People With a Hematologic Malignancy Who Will Receive a Stem Cell Transplant

Recruiting
NCT07548983Phase 1

Ruxolitinib With Azacitidine Maintenance for the Treatment of Patients With Acute Myeloid Leukemia Undergoing Reduced Intensity Allogeneic Stem Cell Transplantation

Recruiting
NCT05805605Phase 2

Allo HSCT Using RIC and PTCy for Hematological Diseases

Recruiting
NCT05039619Phase 2

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants

Recruiting
NCT06996119Phase 1

Emapalumab With Post-Transplant Cyclophosphamide, Tacrolimus and Mycophenolate Mofetil for the Prevention of Graft-versus-Host Disease After Donor Reduced-Intensity Hematopoietic Cell Transplant

Recruiting
NCT07162038Phase 1

Phase I Trial Integrating HLA-Haploidentical Anti-CD19 CAR-T Cells With Post-Transplantation Cyclophosphamide-Based HLA-Haploidentical Hematopoietic Cell Transplantation

Recruiting
NCT05907746Phase 2

Allogeneic Hematopoietic Stem Cell Transplantation With Briquilimab-Based Conditioning in Participants With GATA2 Deficiency

Active Not Recruiting
NCT04877288Phase 3

A Study to Evaluate the Benefits and Risks of Conversion of Existing Adolescent Kidney Transplant Recipients Aged 12 to <18 Years to a Belatacept-based Immunosuppressive Regimen as Compared to Continuation of a Calcineurin Inhibitor-based Regimen, and Their Adherence to Immunosuppressive Medications

Recruiting
NCT02782546Phase 2

Cytokine Induced Memory-like NK Cell Adoptive Therapy After Haploidentical Donor Hematopoietic Cell Transplantation

Active Not Recruiting
NCT07412470Phase 2

A Study to Investigate the Efficacy and Safety of Frexalimab Versus Tacrolimus in Adults Undergoing Kidney Transplantation

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
525