Success Metrics

Clinical Success Rate
79.9%

Based on 306 completed trials

Completion Rate
80%(306/383)
Active Trials
65(12%)
Results Posted
70%(214 trials)
Terminated
77(15%)

Phase Distribution

Ph phase_1
104
20%
Ph early_phase_1
6
1%
Ph phase_2
235
45%
Ph phase_4
72
14%
Ph phase_3
57
11%
Ph not_applicable
38
7%

Phase Distribution

110

Early Stage

235

Mid Stage

129

Late Stage

Phase Distribution512 total trials
Early Phase 1First-in-human
6(1.2%)
Phase 1Safety & dosage
104(20.3%)
Phase 2Efficacy & side effects
235(45.9%)
Phase 3Large-scale testing
57(11.1%)
Phase 4Post-market surveillance
72(14.1%)
N/ANon-phased studies
38(7.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

74.5%

306 of 411 finished

Non-Completion Rate

25.5%

105 ended early

Currently Active

65

trials recruiting

Total Trials

525

all time

Status Distribution
Active(71)
Completed(306)
Terminated(105)
Other(43)

Detailed Status

Completed306
Terminated77
Recruiting42
unknown41
Withdrawn28
Active, not recruiting23

Development Timeline

Analytics

Development Status

Total Trials
525
Active
65
Success Rate
79.9%
Most Advanced
Phase 4

Trials by Phase

Early Phase 16 (1.2%)
Phase 1104 (20.3%)
Phase 2235 (45.9%)
Phase 357 (11.1%)
Phase 472 (14.1%)
N/A38 (7.4%)

Trials by Status

active_not_recruiting234%
enrolling_by_invitation10%
withdrawn285%
unknown418%
terminated7715%
suspended20%
completed30658%
not_yet_recruiting51%
recruiting428%

Recent Activity

Clinical Trials (525)

Showing 20 of 525 trialsScroll for more
NCT07524530Phase 2

Stem Cell Transplantation for Participants With Germline RUNX1 Associated Blood Cancers

Not Yet Recruiting
NCT05785065Phase 2

Mycophenolate Mofetil in Systemic Sclerosis With Subclinical Interstitial Lung Disease

Recruiting
NCT02495077Phase 2

Effects of Inhibiting Early Inflammation in Kidney Transplant Patients

Completed
NCT02711826Phase 1

Treg Therapy in Subclinical Inflammation in Kidney Transplantation

Completed
NCT04066114Phase 1

Treg Modulation With CD28 and IL-6 Receptor Antagonists

Completed
NCT01856257Phase 2

Open-Label Phase 2 Trial of a Steroid-Free, CNI-Free, Belatacept-Based Immunosuppressive Regimen

Terminated
NCT01790594Phase 2

Optimization of NULOJIX® Usage Towards Minimizing CNI Exposure in Simultaneous Pancreas and Kidney Transplantation

Terminated
NCT02782546Phase 2

Cytokine Induced Memory-like NK Cell Adoptive Therapy After Haploidentical Donor Hematopoietic Cell Transplantation

Active Not Recruiting
NCT07162038Phase 1

Phase I Trial Integrating HLA-Haploidentical Anti-CD19 CAR-T Cells With Post-Transplantation Cyclophosphamide-Based HLA-Haploidentical Hematopoietic Cell Transplantation

Recruiting
NCT07412470Phase 2

A Study to Investigate the Efficacy and Safety of Frexalimab Versus Tacrolimus in Adults Undergoing Kidney Transplantation

Recruiting
NCT05327023Phase 1

Donor Lymphocyte Infusion After Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic Malignancies

Recruiting
NCT04375631Phase 1

CLAG-M or FLAG-Ida Chemotherapy and Reduced-Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelomonocytic Leukemia

Recruiting
NCT06055608Phase 2

Advancing Transplantation Outcomes in Children

Recruiting
NCT05807932Phase 1

Venetoclax in Addition to Sequential Conditioning With Fludarabine / Amsacrine / Ara-C (FLAMSA) + Treosulfan for Allogeneic Blood Stem Cell Transplantation in Patients With MDS, CMML or sAML

Recruiting
NCT05538208Phase 2

The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study

Recruiting
NCT06680661Phase 2

ABBA CORD: dCBT w/ Abatacept for aGVHD Prophylaxis

Suspended
NCT05039619Phase 2

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants

Recruiting
NCT07349771Phase 2

Axatilimab Plus Standard of Care Therapy for the Prevention of Graft Versus Host Disease Following Allogeneic Hematopoietic Stem Cell Transplantation in Patients With Hematologic Cancer, ABRAXAS Trial

Withdrawn
NCT04262843Phase 2

Total Marrow and Lymphoid Irradiation as Conditioning Regimen Before Hematopoietic Cell Transplantation in Patients With Myelodysplastic Syndrome or Acute Leukemia

Active Not Recruiting
NCT04877288Phase 3

A Study to Evaluate the Benefits and Risks of Conversion of Existing Adolescent Kidney Transplant Recipients Aged 12 to <18 Years to a Belatacept-based Immunosuppressive Regimen as Compared to Continuation of a Calcineurin Inhibitor-based Regimen, and Their Adherence to Immunosuppressive Medications

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
525