Success Metrics

Clinical Success Rate
79.7%

Based on 303 completed trials

Completion Rate
80%(303/380)
Active Trials
66(13%)
Results Posted
68%(205 trials)
Terminated
77(15%)

Phase Distribution

Ph phase_4
72
14%
Ph phase_1
104
20%
Ph early_phase_1
6
1%
Ph not_applicable
38
7%
Ph phase_2
234
45%
Ph phase_3
57
11%

Phase Distribution

110

Early Stage

234

Mid Stage

129

Late Stage

Phase Distribution511 total trials
Early Phase 1First-in-human
6(1.2%)
Phase 1Safety & dosage
104(20.4%)
Phase 2Efficacy & side effects
234(45.8%)
Phase 3Large-scale testing
57(11.2%)
Phase 4Post-market surveillance
72(14.1%)
N/ANon-phased studies
38(7.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

74.4%

303 of 407 finished

Non-Completion Rate

25.6%

104 ended early

Currently Active

66

trials recruiting

Total Trials

524

all time

Status Distribution
Active(74)
Completed(303)
Terminated(104)
Other(43)

Detailed Status

Completed303
Terminated77
Recruiting42
unknown42
Withdrawn27
Active, not recruiting24

Development Timeline

Analytics

Development Status

Total Trials
524
Active
66
Success Rate
79.7%
Most Advanced
Phase 4

Trials by Phase

Early Phase 16 (1.2%)
Phase 1104 (20.4%)
Phase 2234 (45.8%)
Phase 357 (11.2%)
Phase 472 (14.1%)
N/A38 (7.4%)

Trials by Status

enrolling_by_invitation10%
not_yet_recruiting71%
recruiting428%
suspended10%
unknown428%
withdrawn275%
completed30358%
active_not_recruiting245%
terminated7715%

Recent Activity

Clinical Trials (524)

Showing 20 of 524 trialsScroll for more
NCT07524530Phase 2

Stem Cell Transplantation for Participants With Germline RUNX1 Associated Blood Cancers

Not Yet Recruiting
NCT07566377Phase 2

Cord Blood Transplantation in Children and Young Adults With Blood Cancer

Recruiting
NCT04888741Phase 2

Methods of T Cell Depletion Trial (MoTD)

Recruiting
NCT03670966Phase 1

211At-BC8-B10 Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory High-Risk Acute Leukemia or Myelodysplastic Syndrome

Recruiting
NCT05039619Phase 2

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants

Recruiting
NCT01231412Phase 3

Graft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated Donor Peripheral Blood Stem Cell Transplant

Completed
NCT06807606Phase 2

Optimized Cord Blood Transplantation for the Treatment of Patients With High-risk Hematologic Malignancies Who Have Relapsed After First Allogeneic Stem Cell Transplantation

Recruiting
NCT05327023Phase 1

Donor Lymphocyte Infusion After Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic Malignancies

Recruiting
NCT04959175Phase 1

Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic Malignancies

Recruiting
NCT07162038Phase 1

Phase I Trial Integrating HLA-Haploidentical Anti-CD19 CAR-T Cells With Post-Transplantation Cyclophosphamide-Based HLA-Haploidentical Hematopoietic Cell Transplantation

Recruiting
NCT07412470Phase 2

A Study to Investigate the Efficacy and Safety of Frexalimab Versus Tacrolimus in Adults Undergoing Kidney Transplantation

Recruiting
NCT07548983Phase 1

Ruxolitinib With Azacitidine Maintenance for the Treatment of Patients With Acute Myeloid Leukemia Undergoing Reduced Intensity Allogeneic Stem Cell Transplantation

Not Yet Recruiting
NCT06973668Phase 2

A Randomized Study to Compare Post-transplant Cyclophosphamide, Sirolimus, Ruxolitinib and Post-transplant Cyclophosphamide, Sirolimus, Mycophenolate Mofetil to Prevent Graft Versus Host Disease

Recruiting
NCT07493538Phase 2

MT2025-35 Allogeneic Hematopoietic Stem Cell Transplantation Using Reduced Intensity Conditioning Treosulfan and Fludarabine, With Post-Transplant Cytoxan (PTCy) for the Treatment of Hematological Diseases

Recruiting
NCT07349771Phase 2

Axatilimab Plus Standard of Care Therapy for the Prevention of Graft Versus Host Disease Following Allogeneic Hematopoietic Stem Cell Transplantation in Patients With Hematologic Cancer, ABRAXAS Trial

Not Yet Recruiting
NCT01384513Phase 2

A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies

Completed
NCT03192397Phase 1

Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant

Active Not Recruiting
NCT04384692Phase 2

Peritransplant Ruxolitinib for Patients With Primary and Secondary Myelofibrosis

Active Not Recruiting
NCT04547049Phase 3

A Study Comparing Haploidentical Hematopoietic Stem Cell Transplantations (HSCTs) From Young Non-first-degree and Older First-degree Donors in Hematological Malignancies

Active Not Recruiting
NCT05736419Phase 2

A Study of Immune Suppression Treatment for People With Sickle Cell Disease or β-Thalassemia Who Are Going to Receive an Allogeneic Hematopoietic Cell Transplantation (HCT)

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
524