Prefrontal Cortex and Abstract Thinking
Neuropsychological and Anatomical Study of Concept Formation in Frontal Patients
1 other identifier
observational
69
1 country
1
Brief Summary
The capacity of concept formation is not well understood, even if a link is supposed with the functioning of the frontal lobes. Our aim is to better understand the cognitive mechanisms underlying this function and to try to correlate the performance with atrophy of the frontal lobe in neurodegenerative diseases involving this region (frontotemporal lobar degeneration and progressive supranuclear palsy).
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Apr 2010
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 1, 2010
CompletedFirst Submitted
Initial submission to the registry
April 7, 2010
CompletedFirst Posted
Study publicly available on registry
April 8, 2010
CompletedStudy Completion
Last participant's last visit for all outcomes
April 1, 2011
CompletedDecember 9, 2011
December 1, 2011
April 7, 2010
December 8, 2011
Conditions
Keywords
Study Arms (3)
PSP (Progressive supranuclear palsy)
FTD (Frontotemporal lobar degenerative)
Alzheimer's disease
Interventions
Examination including especially concept formation
MRI performed in T1-weighted three dimensional sequence
Eligibility Criteria
3 groups including : PSP, FTD, AD
You may qualify if:
- informed consent signed
- MMSE\> 20
- No contra indication to MRI
You may not qualify if:
- MMSE\<20
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Inserm U 975
Paris, 75013, France
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Richard Levy, MD
Institut National de la Santé Et de la Recherche Médicale, France
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER GOV
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
April 7, 2010
First Posted
April 8, 2010
Study Start
April 1, 2010
Study Completion
April 1, 2011
Last Updated
December 9, 2011
Record last verified: 2011-12