Long Term Physical Training in Asthma
Effects of Long Term Physical Training Once a Week on Fitness and Quality of Life in Elderly Asthmatics
1 other identifier
interventional
24
1 country
1
Brief Summary
This controlled study is undertaken to investigate the effects of a long term outpatient training program on physical fitness and quality of life in elderly asthmatics.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable asthma
Started Apr 1996
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 1, 1996
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 1, 1998
CompletedStudy Completion
Last participant's last visit for all outcomes
March 1, 1998
CompletedFirst Submitted
Initial submission to the registry
March 31, 2010
CompletedFirst Posted
Study publicly available on registry
April 1, 2010
CompletedApril 1, 2010
March 1, 2010
1.8 years
March 31, 2010
March 31, 2010
Conditions
Outcome Measures
Primary Outcomes (1)
Maximum oxygen uptake
Maximum oxygen uptake measured during unsteady state cycle ergometer test with work increments of 10 watts each minute until exhaustion.
One year
Secondary Outcomes (2)
General quality of life
One year
Disease-specific quality of life
One year
Study Arms (2)
Exercise training
ACTIVE COMPARATORSubjects participate in a once weekly supervised exercise training group, duration of 60 min.
Control
NO INTERVENTIONControl group receives no intervention
Interventions
Exercise training in outpatient sport groups once weekly with a duration of 60 min each
Eligibility Criteria
You may qualify if:
- physician diagnosed asthma
- non-smoker
- stable condition
- informed consent
You may not qualify if:
- unability to attend training sessions on a regular basis for one year
- symptomatic coronary heart disease
- uncontrolled heart failure
- hemodynamically relevant cardiac rhythm disorders
- hemodynamically relevant cardiac valvular disorders
- uncontrolled arterial hypertension
- hypercapnic respiratory failure
- severe hypoxemia (i.e. PaO2 \<50 mm Hg resp. SaO2 \<80% at rest)
- history of decompensated right heart failure
- pulmonary arterial hypertension (PA mean pressure at rest \>20 mm Hg)
- severe osteoporosis
- severe airway obstruction (FEV1 \<50% predicted, FEV1 \<60% predicted following bronchodilatation)
- maximum work rate of less than 50 watt during ergometer testing
- uncontrolled asthma
- COPD exacerbation
- +1 more criteria
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University Medical Center Hamburg-Eppendorf
Hamburg, Germany
Related Publications (1)
Meyer A, Gunther S, Volmer T, Taube K, Baumann HJ. A 12-month, moderate-intensity exercise training program improves fitness and quality of life in adults with asthma: a controlled trial. BMC Pulm Med. 2015 May 7;15:56. doi: 10.1186/s12890-015-0053-8.
PMID: 25947010DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Andreas Meyer, M.D.
Kliniken Mariahilf GmbH, Mönchengladbach, Germany
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
March 31, 2010
First Posted
April 1, 2010
Study Start
April 1, 1996
Primary Completion
January 1, 1998
Study Completion
March 1, 1998
Last Updated
April 1, 2010
Record last verified: 2010-03