NCT01095341

Brief Summary

The purpose of this study is to evaluate the frequency and the clinical course of postoperative hyperthyroidism following surgery of tertiary hyperparathyroidism (THP) and to determine the diagnostic value of thyroglobulin in this setting.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
57

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Apr 2008

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2008

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2009

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2009

Completed
12 months until next milestone

First Submitted

Initial submission to the registry

March 29, 2010

Completed
1 day until next milestone

First Posted

Study publicly available on registry

March 30, 2010

Completed
Last Updated

March 30, 2010

Status Verified

March 1, 2010

Enrollment Period

1 year

First QC Date

March 29, 2010

Last Update Submit

March 29, 2010

Conditions

Hyperthyroidism

Keywords

hyperthyroidismtertiary hyperparathyroidismpalpation thyroiditisparathyroidectomythyroglobulinrate of postoperative hyperthyroidism

Outcome Measures

Primary Outcomes (1)

  • Hyperthyroidism

Secondary Outcomes (1)

  • Thyroglobulin elevation

Study Arms (2)

THP

THP: patients undergoing parathyroidectomy according to tertiary hyperparathyroidism

Other: No intervention performed

Other causes

patients with hyperthyroidism not caused by parathyroidectomy

Other: No intervention performed

Interventions

No intervention performedOTHER
Other causesTHP

Eligibility Criteria

Age18 Years - 90 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

patients with tertiary hyperparathyroidism undergoing surgery for this reason

You may qualify if:

  • patients with tertiary hyperparathyroidism undergoing surgery for this reason
  • dialysis treatment

You may not qualify if:

  • patients wish

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospital Heidelberg

Heidelberg, 69120, Germany

Location

Related Publications (1)

  • Rudofsky G Jr, Grafe IA, Metzner C, Leowardi C, Fohr B. Transient post-operative thyrotoxicosis after parathyroidectomy. Med Sci Monit. 2009 Mar;15(3):CS41-3.

    PMID: 19247247BACKGROUND

MeSH Terms

Conditions

Hyperthyroidism

Condition Hierarchy (Ancestors)

Thyroid DiseasesEndocrine System Diseases

Study Officials

  • Gottfried Rudofsky, MD

    University Hospital Heidelberg Germany

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

March 29, 2010

First Posted

March 30, 2010

Study Start

April 1, 2008

Primary Completion

April 1, 2009

Study Completion

April 1, 2009

Last Updated

March 30, 2010

Record last verified: 2010-03

Locations

DE(1)