NCT01093599

Brief Summary

The Mindfulness Training for Smokers study follows a randomized controlled design with 240 total participants. Both the study group and the control group will be enrolled in the Wisconsin Tobacco Quit Line and will receive four weeks of nicotine patches. The control group will receive the Quit Line intervention alone where as the study group will receive the Quit Line intervention plus the Mindfulness for Smokers Intervention. The Mindfulness for Smokers Intervention provides four weeks of instruction in mindfulness meditation followed by four weeks of participation in a weekly meditation group. The principal hypothesis for the study is that Mindfulness for Smokers plus the Quit Line will lead to significantly higher rates of smoking cessation at 6 months than the Quit Line alone.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
196

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Mar 2010

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2010

Completed
23 days until next milestone

First Submitted

Initial submission to the registry

March 24, 2010

Completed
2 days until next milestone

First Posted

Study publicly available on registry

March 26, 2010

Completed
3.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2013

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2013

Completed
1.2 years until next milestone

Results Posted

Study results publicly available

February 16, 2015

Completed
Last Updated

October 20, 2015

Status Verified

January 1, 2015

Enrollment Period

3.8 years

First QC Date

March 24, 2010

Results QC Date

May 17, 2014

Last Update Submit

September 30, 2015

Conditions

Keywords

SmokingSmoking cessationNicotineTobaccoMindfulnessMeditationMBSRMindfulness TrainingBehavioral InterventionNicotine PatchQuit LinePhone counseling

Outcome Measures

Primary Outcomes (1)

  • Smoking Abstinence

    Smoking abstinence is measured by Carbon Monoxide Breath Testing in Controls vs Study Group subjects six months after the quit day.

    6 months post quit day

Secondary Outcomes (1)

  • Changes in Self Reported Measures of Depression, Anxiety and Stress in Study Subjects vs Controls

    6 months post quit day

Study Arms (2)

Quit Line Only

ACTIVE COMPARATOR

Control Participants will call the Wisconsin Tobacco Quit Line intervention including phone counseling, Quit Smoking Materials and 4 weeks of nicotine patches.

Behavioral: Quit Line Only

Quit Line plus MTS

ACTIVE COMPARATOR

Participants in the study group will receive the Quit Line intervention (talk to a Quit Line Counselor, receive quit smoking materials and get 4 weeks of nicotine patches) and also receive 4 weeks of training in mindfulness meditation through the mindfulness for smokers intervention.

Behavioral: Quit Line plus MTS

Interventions

This provides the quit line intervention plus the Mindfulness for Smokers Intervention.

Also known as: Study Group, Quit Line Plus Mindfulness Training for Smokers
Quit Line plus MTS
Quit Line OnlyBEHAVIORAL

The quit line only intervention includes phone counseling, Quit Smoking Materials and 4 weeks of nicotine patches.

Also known as: Control Group
Quit Line Only

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age: 18 years or over;
  • Participants must express "high" motivation to quit smoking
  • Participants must express willingness to attend "all" meetings for 2 months.
  • Smoke 5 or more cigarettes per day

You may not qualify if:

  • Self report of alcohol use of 4 drinks or more a night on 4 or more nights per week.
  • Self report of using chewing tobacco, snuff or cigars in the last week.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Wisconsin School of Medicine and Public Health Center for Tobacco Research and Intervention

Madison, Wisconsin, 53711, United States

Location

Related Publications (2)

  • Davis JM, Goldberg SB, Anderson MC, Manley AR, Smith SS, Baker TB. Randomized trial on mindfulness training for smokers targeted to a disadvantaged population. Subst Use Misuse. 2014 Apr;49(5):571-85. doi: 10.3109/10826084.2013.770025.

  • Jackson S, Brown J, Norris E, Livingstone-Banks J, Hayes E, Lindson N. Mindfulness for smoking cessation. Cochrane Database Syst Rev. 2022 Apr 14;4(4):CD013696. doi: 10.1002/14651858.CD013696.pub2.

Related Links

MeSH Terms

Conditions

Tobacco Use DisorderSmokingSmoking Cessation

Interventions

Control Groups

Condition Hierarchy (Ancestors)

Substance-Related DisordersChemically-Induced DisordersMental DisordersBehaviorHealth Behavior

Intervention Hierarchy (Ancestors)

Epidemiologic Research DesignEpidemiologic MethodsInvestigative TechniquesResearch DesignMethods

Limitations and Caveats

A principal limitation of this study is that it is designed to compare MTS to a less intensive usual care therapy and as such lacks a time/intensity matched control.

Results Point of Contact

Title
James M. Davis MD, Assistant Professor, Duke University
Organization
University of Wisconsin

Study Officials

  • James M Davis, MD

    University of Wisconsin, Madison

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 24, 2010

First Posted

March 26, 2010

Study Start

March 1, 2010

Primary Completion

December 1, 2013

Study Completion

December 1, 2013

Last Updated

October 20, 2015

Results First Posted

February 16, 2015

Record last verified: 2015-01

Locations