NCT01088139

Brief Summary

This is a randomized controlled, observer blinded trial to study the beneficial effect of nutritional supplementation in elderly Hong Kong patients after hip fracture surgery during rehabilitation and at 4 weeks follow up. The control group will receive Calcium and Vitamin D supplementation whereas the intervention group will receive a moderately high dose protein nutritional supplementation in addition to Vitamin D and Calcium. Both groups undergo the same rehabilitation program and dietary counseling before discharge. They are followed up 4 weeks after discharge or completion of supplementation. The outcome parameters are nutritional parameters and rehabilitation outcomes.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
126

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Nov 2008

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2008

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2010

Completed
15 days until next milestone

First Submitted

Initial submission to the registry

March 16, 2010

Completed
1 day until next milestone

First Posted

Study publicly available on registry

March 17, 2010

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2011

Completed
Last Updated

May 4, 2011

Status Verified

April 1, 2011

Enrollment Period

1.3 years

First QC Date

March 16, 2010

Last Update Submit

May 3, 2011

Conditions

Keywords

Nutritional supportRehabilitation outcomes

Outcome Measures

Primary Outcomes (1)

  • Nutritional parameters

    Biochemical and anthropometric measurements

    Change from Baseline in nutritional parameters at discharge from hospital and at 4 weeks after discharge

Secondary Outcomes (1)

  • Rehabilitation Outcomes

    Change from Baseline in rehabilitation outcomes at discharge from hospital and at 4 weeks after discharge

Study Arms (2)

Control

NO INTERVENTION

Nutritional Supplementation

EXPERIMENTAL
Dietary Supplement: Protein supplementation

Interventions

Protein supplementationDIETARY_SUPPLEMENT

Ready made protein supplement drinks with approximate protein content of 18-24g per 500ml per day. Caloric content is 490 to 530Kcal depending on the brand of drink.

Also known as: Ensure (Abbott), Resource Breeze (Nestle Nutrition), Compleat (Nestle Nutrition), Glucerna (Abbott)
Nutritional Supplementation

Eligibility Criteria

Age60 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age 60 years or older
  • Recent low impact osteoporotic fracture of the proximal femur surgically repaired within 4 weeks before recruitment

You may not qualify if:

  • Patients who require tube feeding
  • Patients in unstable medical condition
  • Body mass index (BMI) ≧ 25
  • Malignancy
  • Conditions with contraindication for high protein diet
  • Mentally incapacitated and inability to communicate or understand the consent.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Rehabilitation, Kowloon Hospital

Kowloon, Hong Kong

Location

MeSH Terms

Conditions

Hip Fractures

Interventions

Glucerna

Condition Hierarchy (Ancestors)

Femoral FracturesFractures, BoneWounds and InjuriesHip InjuriesLeg Injuries

Study Officials

  • Ma Wai Wai MYINT, MBBS

    Kowloon Hospital, Hong Kong

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

March 16, 2010

First Posted

March 17, 2010

Study Start

November 1, 2008

Primary Completion

March 1, 2010

Study Completion

April 1, 2011

Last Updated

May 4, 2011

Record last verified: 2011-04

Locations