NCT00664950

Brief Summary

Elderly patients with an intertrochanteric hip fracture will be randomized to receive either a sliding hip screw (SHS) (control group) or InterTAN intermedullary nail (IMN) (experimental group) for surgical fixation of their hip fracture. This study will assess functional and mortality outcomes for elderly patients with hip fractures.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
240

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Nov 2007

Longer than P75 for not_applicable

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2007

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

April 18, 2008

Completed
5 days until next milestone

First Posted

Study publicly available on registry

April 23, 2008

Completed
6.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2014

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2014

Completed
Last Updated

September 2, 2015

Status Verified

September 1, 2015

Enrollment Period

6.8 years

First QC Date

April 18, 2008

Last Update Submit

September 1, 2015

Conditions

Keywords

intertrochanteric hip fracture fixationinterTAN IM Nailsliding hip screw

Outcome Measures

Primary Outcomes (2)

  • Functional Independence Measure (FIM)

    prospective

  • Timed up an go (TUG)

    prospective

Secondary Outcomes (7)

  • 2-minute walk test (2MWT)

    prospective

  • Geriatric Depression Scale (GDS)

    prospective

  • Lower Extremity Measure (LEM)

    prospective

  • Complications

    prospective

  • Femoral shortening

    prospective

  • +2 more secondary outcomes

Study Arms (2)

SHS

ACTIVE COMPARATOR

sliding hip screw

Device: sliding hip screw

InterTAn IM Nail

ACTIVE COMPARATOR

interTAN IM nail

Device: IntertAn IM nail

Interventions

surgical repair of hip fracture using conventional sliding hip screw

SHS

interTAN IM nail

Also known as: InterTAn
InterTAn IM Nail

Eligibility Criteria

Age55 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age 55 years or greater\*
  • Intertrochanteric fracture amenable to treatment by sliding hip screw or intramedullary nail fixation
  • Previously ambulatory (defined as not usually requiring a wheelchair for ambulation)\*
  • Provision of informed consent\*
  • Surgery performed within 72 hours of admission

You may not qualify if:

  • Cognitive or language barriers that would limit completion of assessment tests in English\*
  • Anticipated problems with follow-up in the judgment of the resident, or attending surgeon (e.g of no fixed address)\*
  • Surgeon refusal to randomize patient
  • Pathologic fractures
  • Polytrauma that would impact functional assessments in the opinion of the surgeon

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Saint John Regional Hosptial

Saint John, New Brunswick, Canada

Location

London Health Sciences Centre

London, Ontario, N6A 4G5, Canada

Location

Ottawa Civic Hospital

Ottawa, Ontario, Canada

Location

MeSH Terms

Conditions

Hip Fractures

Condition Hierarchy (Ancestors)

Femoral FracturesFractures, BoneWounds and InjuriesHip InjuriesLeg Injuries

Study Officials

  • David Sanders, MD

    London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

    PRINCIPAL INVESTIGATOR
  • Dianne Bryant

    Western University, Canada

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD

Study Record Dates

First Submitted

April 18, 2008

First Posted

April 23, 2008

Study Start

November 1, 2007

Primary Completion

August 1, 2014

Study Completion

December 1, 2014

Last Updated

September 2, 2015

Record last verified: 2015-09

Locations