DETECT-Diabetes Cardiovascular Risk-Evaluation: Targets and Essential Data for Commitment of Treatment

NCT01076608 | Completed DMC

• 1 other identifier: 149092003
• Study Type: observational
• Target: 55,518
• Locations: 0 countries
• Sites: N/A

Brief Summary

Cardiovascular diseases are, along with cancer, the most frequent causes for mortality and morbidity in the industrialized nations. Numerous clinical efficient approaches to reduce the known risk factors have been introduced in clinical routine care; yet with quite limited success, e.g. modification of behavioral risk factors, drug treatment and the combination of both. On the population level only marginal changes have been demonstrated, i.e. the mortality from myocardial infarction and stroke remains high. To answer questions about underlying factors, for this unsatisfactory status, we might profit tremendously from studies that examine the situation, where treatment of patients most frequently take place: in primary care. This approach pays attention to the General Practitioner's (GP) in their gate keeping function in health care. Information from primary care in particular is largely lacking as recently stated by the "Sachverständigenrat für die konzertierte Aktion im Gesundheitswesen" in 2001. The DETECT study has been designed to address these critical issues. On 16th and 18th September 2003, 3,188 GPs completed a standardised assessment of the diagnostic and therapeutic profile of 55,518 unselected consecutive patients. All patients completed a questionnaire on their demographic data, their complaints, their illness history, their knowledge about selected diseases and their attitude towards those. A sub sample of 7,519 patients additionally attended a standardized laboratory screening program. In this screening the focus was on blood constituents connected with cardiovascular diseases and diabetes, including e. g. cholesterol, lipoproteins, triglycerides and HbA1c. These patients were assessed a second time in the follow up period after one year in 2004 and for a final time after completion of the five-year follow-up period.

Conditions

Cardiovascular Diseases

Keywords

primary care patients

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Representative random sample of 3188 General Practitioners in Germany (general practitioners and internists serving as GPs), who included patients: * Main study: 55,518 (unselected consecutive) * Longitudinal observation study in a random subset of 7519 patients

You may qualify if:

• unselected primary care patients

You may not qualify if:

• none

Sponsors & Collaborators

• Technische Universität Dresden: lead
• Johann Wolfgang Goethe University Hospital: collaborator
• Max-Planck-Institute of Psychiatry: collaborator
• University of Magdeburg: collaborator
• Medical University of Graz: collaborator
• Universitätsklinikum Hamburg-Eppendorf: collaborator

Related Publications (1)

• Wittchen HU, Glaesmer H, Marz W, Stalla G, Lehnert H, Zeiher AM, Silber S, Koch U, Bohler S, Pittrow D, Ruf G; DETECT-Study Group. Cardiovascular risk factors in primary care: methods and baseline prevalence rates--the DETECT program. Curr Med Res Opin. 2005 Apr;21(4):619-30. doi: 10.1185/030079905X38187.

  PMID: 15899112 BACKGROUND

Related Links

• Study homepage

Biospecimen

Retention: SAMPLES WITHOUT DNA

whole blood, serum

MeSH Terms

Conditions

Cardiovascular Diseases

Study Officials

• Hans-Ullrich Wittchen, Prof. Dr.

  Director of the Institute of Clinical Psychology and Psychotherapy at the Technical University of Dresden

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: February 25, 2010
• First Posted: February 26, 2010
• Study Start: September 1, 2003
• Primary Completion: September 1, 2008
• Study Completion: December 1, 2008
• Last Updated: February 26, 2010

Record last verified: 2010-02