NCT01067885

Brief Summary

The MARIS Register is a prospective, multicenter registry of implantation in the superficial femoral artery (SFA) with a CE marked stent (Maris / Invatec) intended to capture initial angiographic success, complication rate and symptomatic related revascularization by following the clinical process and duplex examinations at 6 and 12 month.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,051

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Apr 2006

Longer than P75 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2006

Completed
3.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2009

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2009

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

February 11, 2010

Completed
1 day until next milestone

First Posted

Study publicly available on registry

February 12, 2010

Completed
Last Updated

April 12, 2012

Status Verified

April 1, 2012

Enrollment Period

3.7 years

First QC Date

February 11, 2010

Last Update Submit

April 11, 2012

Conditions

Keywords

Nitinol StentSuperficial femoral arterySFAAngioplastyperipheral artery diseaseperipheral artery obstructive diseasePAODPADPeripheral Vascular Disease

Outcome Measures

Primary Outcomes (1)

  • target lesion revascularization

    1 year

Secondary Outcomes (8)

  • Restenosis rate > 50% according to ultrasound criteria

    6 and 12 month

  • Restenosis rate > 70% according to ultrasound criteria

    6 and 12 month

  • Location of restenosis (proximal, middle, distal AFS)

    6 and 12 month

  • Number of stent fractures (grading according to FESTO criteria)

    12 month

  • Procedure related complication rate

    Discharge

  • +3 more secondary outcomes

Interventions

stenting of SFA with Maris nitinol stent/s

Also known as: Maris nitinol stent (Invatec, Italy)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • stent implantation in SFA is possible
  • existing SFA stenosis 70-100 % (visual estimation)
  • absence of homodynamically relevant stenosis in A. poplitea
  • at least one lower limb run off vessel

You may not qualify if:

  • pregnancy
  • life expectancy less than 1 year
  • coagulation disorder
  • chronic anticoagulation therapy
  • active gastrointestinal bleeding
  • thrombolytic therapy within 72 hours before intervention
  • hyperthyreosis
  • severe contrast agent allergy
  • allergy to concomittant medication
  • severe liver disease
  • thrombus in target lesion
  • target lesion extend into A. poplitea
  • severe calcification of target vessel, where no successful pre-dilatation is feasible

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Krankenberg H, Tubler T, Sixt S, Fischer M, Schmiedel R, Schulte KL, Balzer JO, Kieback A, Fiehn E, Wittenberg G, Ali T, Tiefenbacher C, Jahnke T, Steinkamp HJ, Wegscheider K, Treszl A, Ingwersen M, Zeller T. German multicenter real-world registry of stenting for superficial femoral artery disease: clinical results and predictive factors for revascularization. J Endovasc Ther. 2014 Aug;21(4):463-71. doi: 10.1583/13-4625R.1.

MeSH Terms

Conditions

Peripheral Arterial DiseasePeripheral Vascular Diseases

Condition Hierarchy (Ancestors)

AtherosclerosisArteriosclerosisArterial Occlusive DiseasesVascular DiseasesCardiovascular Diseases

Study Officials

  • Hans Krankenbeg, MD

    MCC Prof. Mathey, Prof. Schofer

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 11, 2010

First Posted

February 12, 2010

Study Start

April 1, 2006

Primary Completion

December 1, 2009

Study Completion

December 1, 2009

Last Updated

April 12, 2012

Record last verified: 2012-04