Adapted Cardiac Rehabilitation After Stroke

NCT01067495 | Completed Phase 1

• 1 other identifier: HSFO-SRA5977
• Study Type: interventional
• Target: 43
• Locations: 1 country
• Sites: 1

Brief Summary

Despite the similarities between heart disease and stroke in terms of disease process and elevated risk of recurrent events, exercise-based programs akin to cardiac rehabilitation are not available for people with stroke. The purpose of this study is to examine 1) the feasibility of adapting cardiac rehabilitation for individuals with stroke, and 2) the effects of this program on aerobic capacity, walking, risk factors, community integration and quality of life. The investigators anticipate that cardiac rehabilitation may be appropriately adapted to accommodate individuals with stroke who have a range of functional abilities, and that this program is effective in improving aerobic capacity, walking ability and stroke risk factors. The investigators also anticipate participants will demonstrate improved community integration and quality of life following this program.

Conditions

Stroke

Keywords

stroke; rehabilitation; exercise; walking; risk factors

Outcome Measures

Primary Outcomes (1)

• Cardiorespiratory fitness (aerobic capacity) and walking capacity (6 minute walk test, spatiotemporal gait parameters)

  Pre-baseline (-3 months), pre-program (0 months), post-program (6 months), follow up (12 months)

Secondary Outcomes (1)

• Plasma lipid analysis, questionnaires pertaining to quality of life and community integration

  Pre-baseline (-3 months), pre-program (0 months), post-program (6 months), follow up (12 months)

Study Arms (1)

Exercise

EXPERIMENTAL

Behavioral: Cardiac rehabilitation

Interventions

Cardiac rehabilitation BEHAVIORAL

Participants will participate in a 6-month cardiac rehabilitation exercise program. This program will include aerobic and resistance training, and education sessions on risk factor management.

Exercise

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Chedoke-McMaster Stroke Assessment (CMSA) Scale Leg Score between 3 and 7
• At least 3 months post-stroke
• Ability to understand the process and instructions for exercise training and provide informed consent
• Ability to complete 6-minute walk test

You may not qualify if:

• Resting blood pressure greater than 160/100 despite medication
• Other cardiovascular morbidity which would limit exercise tolerance (heart failure, abnormal blood pressure responses or ST-segment depression \> 2 mm, symptomatic aortic stenosis, complex arrhythmias)
• Unstable angina
• Orthostatic blood pressure decrease of \> 20 mm Hg with symptoms
• Hypertrophic cardiomyopathy
• Other musculoskeletal impairments which would limit the participant's ability to cycle or walk
• Pain or other co-morbidities (e.g. unclipped aneurysms, uncontrolled seizures etc.) which would preclude participation
• Cognitive and/or behavioural issues that would limit participation in exercise testing and training

Sponsors & Collaborators

• Toronto Rehabilitation Institute: lead
• Heart and Stroke Foundation of Ontario: collaborator

Study Sites (1)

Toronto Rehabilitation Institute Cardiac Rehabilitation and Secondary Prevention Program - Rumsey Centre

Toronto, Ontario, M4G 1R7, Canada

Location

Related Publications (1)

• Tang A, Marzolini S, Oh P, McIlroy WE, Brooks D. Feasibility and effects of adapted cardiac rehabilitation after stroke: a prospective trial. BMC Neurol. 2010 Jun 9;10:40. doi: 10.1186/1471-2377-10-40.

  PMID: 20529376 DERIVED

MeSH Terms

Conditions

Stroke; Motor Activity

Interventions

Cardiac Rehabilitation

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases; Behavior

Intervention Hierarchy (Ancestors)

Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Health Services; Health Care Facilities Workforce and Services

Study Officials

• William E McIlroy, PhD

  University of Waterloo

  PRINCIPAL INVESTIGATOR

• Paul Oh, MD

  Toronto Rehabilitation Institute

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: phase 1
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: February 8, 2010
• First Posted: February 11, 2010
• Study Start: January 1, 2006
• Primary Completion: December 1, 2009
• Study Completion: December 1, 2009
• Last Updated: February 11, 2010

Record last verified: 2010-02

Locations

CA (1)