NCT01066780

Brief Summary

The purpose of this study is to collect information about how the new sound-processing affects the ability to hear in everyday listening situations.

Trial Health

90
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
48

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Mar 2010

Shorter than P25 for not_applicable

Geographic Reach
2 countries

11 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 9, 2010

Completed
1 day until next milestone

First Posted

Study publicly available on registry

February 10, 2010

Completed
19 days until next milestone

Study Start

First participant enrolled

March 1, 2010

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2010

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2010

Completed
2.2 years until next milestone

Results Posted

Study results publicly available

October 25, 2012

Completed
Last Updated

July 22, 2020

Status Verified

October 1, 2012

Enrollment Period

6 months

First QC Date

February 9, 2010

Results QC Date

May 1, 2012

Last Update Submit

July 8, 2020

Conditions

Keywords

cochlear implantadultsHiResolutionFidelity 120listening benefitsnoisecochlear implant benefit

Outcome Measures

Primary Outcomes (1)

  • Speech Perception of Standardized Sentences Presented From Recorded Format in Speech-spectrum Noise

    This was a within subjects design where scores on the AzBio sentence test in speech spectrum noise were compared against quiet scores at the 2-Week and 4-Week Follow-up Visit. The AzBio corpus of sentences consists of 33 lists of 20 sentences each (6 to 10 words per sentence) that have been equated for intelligibility. Two AzBio sentence lists were scored at each follow-up visit (2-Week and 4-Week) with either ClearVoice MEDIUM or ClearVoice HIGH enabled and averaged together. Two AzBio sentence lists were also administered in quiet at each visit. The ClearVoice score minus the quiet score provided the difference in score for the analysis.

    4 Weeks

Secondary Outcomes (1)

  • The AzBio Sentences Will be Administered in Recorded Format in Multi-talker Babble.

    2-4 weeks

Study Arms (2)

Group A: ClearVoice Medium

EXPERIMENTAL

Chronic use of ClearVoice MEDIUM for two weeks followed by chronic use of ClearVoice HIGH for two weeks.

Device: ClearVoice

Group B: ClearVoice High

EXPERIMENTAL

Chronic use of ClearVoice HIGH for two weeks followed by chronic use of ClearVoice MEDIUM for two weeks.

Device: ClearVoice

Interventions

ClearVoice is a sound processing strategy designed to improve listening ability in some challenging everyday listening environments for users of the Harmony® HiResolution® Bionic Ear System (Harmony®)

Group A: ClearVoice MediumGroup B: ClearVoice High

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Post-lingually deafened,
  • experienced (6 months device use),
  • adult users of the Harmony HiResolution Bionic Ear System and HiRes Fidelity 120 sound processing.
  • English language proficiency

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (11)

House Ear Clinic

Los Angeles, California, 90057, United States

Location

Carle Clinic Association

Urbana, Illinois, 61801, United States

Location

University of Kentucky

Lexington, Kentucky, 40506-9983, United States

Location

The Johns Hopkins University

Baltimore, Maryland, 21205, United States

Location

Mayo Clinic

Rochester, Minnesota, 55905, United States

Location

Midwest Ear Institute

Kansas City, Missouri, 64111, United States

Location

Washington University Medical Center

St Louis, Missouri, 63110, United States

Location

Medical University of South Carolina

Charleston, South Carolina, 29425, United States

Location

Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States

Location

Nova Scotia Hearing and Speech Centres

Halifax, Nova Scotia, B3J 3R4, Canada

Location

Sunnybrook Health Sciences Centre

Toronto, M4N 3M5, Canada

Location

Results Point of Contact

Title
Kenneth Ripley, Director of Clinical Research
Organization
Advanced Bionics, LLC

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 9, 2010

First Posted

February 10, 2010

Study Start

March 1, 2010

Primary Completion

September 1, 2010

Study Completion

September 1, 2010

Last Updated

July 22, 2020

Results First Posted

October 25, 2012

Record last verified: 2012-10

Locations