NCT01061021

Brief Summary

HIV prevention interventions are needed to assist people living with HIV/AIDS to adhere to their medications and not transmit the virus to others. This study is testing a behavioral intervention designed to address both medication adherence and risk reduction in people living with HIV/AIDS. It is hypothesized that the experimental behavioral intervention will show improved medication adherence and safer sexual behaviors compared to a comparison group.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
490

participants targeted

Target at P75+ for phase_2 hiv-infections

Timeline
Completed

Started Mar 2005

Longer than P75 for phase_2 hiv-infections

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2005

Completed
4.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2009

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

February 1, 2010

Completed
1 day until next milestone

First Posted

Study publicly available on registry

February 2, 2010

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2010

Completed
Last Updated

November 17, 2010

Status Verified

November 1, 2010

Enrollment Period

4.6 years

First QC Date

February 1, 2010

Last Update Submit

November 15, 2010

Conditions

Keywords

HIV preventionTreatment adherenceTreatment for Prevention

Outcome Measures

Primary Outcomes (2)

  • Computerized Interview or Sexual Transmission Risk Behavior

    Baseline, 3, 6 and 9 months

  • Unannounced Phone Based Pill Counts for Medication Adherence

    Baseline, 3, 6, 9 months

Secondary Outcomes (1)

  • Infectiousness Beliefs

    Baseline, 3, 6, and 9 months

Study Arms (2)

Integrated Intervention

EXPERIMENTAL

Five small group + 2 individual counseling behavioral intervention to simultaneously address HIV transmission risk reduction and HIV treatment adherence in men and women living with HIV/AIDS.

Behavioral: In The Mix

Comparison Group

ACTIVE COMPARATOR

Five small group + 2 individual counseling session intervention that serves as an attention control group. Content included stress reduction, nutrition, and exercise for health improvement.

Behavioral: Information Support Group

Interventions

In The MixBEHAVIORAL

Five small group + 2 individual counseling intervention designed to addresses HIV transmission risk behavior and HIV treatment adherence in men and women living with HIV/AIDS.

Integrated Intervention

Five small group + 2 individual counseling session intervention that serves as an attention control group. Content included stress reduction, nutrition, and exercise for health improvement.

Comparison Group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age 18 years or older,
  • Tested HIV positive,
  • Able to provide informed consent.

You may not qualify if:

  • Significant cognitive impairment.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Southeast HIV/AIDS Research and Evaluation Project

Atlanta, Georgia, 30308, United States

Location

MeSH Terms

Conditions

HIV InfectionsTreatment Adherence and Compliance

Condition Hierarchy (Ancestors)

Blood-Borne InfectionsCommunicable DiseasesInfectionsSexually Transmitted Diseases, ViralSexually Transmitted DiseasesLentivirus InfectionsRetroviridae InfectionsRNA Virus InfectionsVirus DiseasesGenital DiseasesUrogenital DiseasesImmunologic Deficiency SyndromesImmune System DiseasesHealth BehaviorBehavior

Study Officials

  • Seth C Kalichman, PhD

    University of Connecticut

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

February 1, 2010

First Posted

February 2, 2010

Study Start

March 1, 2005

Primary Completion

October 1, 2009

Study Completion

August 1, 2010

Last Updated

November 17, 2010

Record last verified: 2010-11

Locations