Mindfulness Meditation Training in HIV
MBSR
Biobehavioral Effects of Mindfulness-Based Stress Reduction in HIV
2 other identifiers
interventional
50
1 country
1
Brief Summary
The purpose of this study is to investigate whether Mindfulness-Based Stress Reduction (MBSR) vs a one-day MBSR seminar improves immune (CD4+ T lymphocytes) and virological (HIV viral load) status in HIV-1 infected adults. The secondary goal of the study is to determine if MBSR vs a one-day MBSR seminar improves self-reported HIV-related quality of life.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for phase_2 hiv-infections
Started Jun 2005
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 1, 2005
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2007
CompletedStudy Completion
Last participant's last visit for all outcomes
January 1, 2008
CompletedFirst Submitted
Initial submission to the registry
January 14, 2008
CompletedFirst Posted
Study publicly available on registry
January 25, 2008
CompletedJanuary 25, 2008
January 1, 2008
2.5 years
January 14, 2008
January 14, 2008
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
CD4+ T lymphocytes (counts)
Pre-test and post-test
Secondary Outcomes (2)
HIV-related Quality of Life
Pre-test and post-test
HIV viral load
Pre-test and post-test
Study Arms (2)
1-Day MBSR
ACTIVE COMPARATOROne-day condensed MBSR class
8-week MBSR
EXPERIMENTAL8-week Mindfulness-Based Stress Reduction Intervention
Interventions
Mindfulness-Based Stress Reduction Intervention
Eligibility Criteria
You may qualify if:
- Diagnosed HIV for \> 6 months
- English speaking
- years old or older
- Indicate some distress (\>4 on the Patient Health Questionnaire-9)
- Willing to be randomized
You may not qualify if:
- Any substance abuse or treatment for a psychiatric disorder in the past 30 days
- Currently diagnosed with AIDS or had CD4+ T lymphocytes \<200 cells
- Hepatitis (A, B, or C)
- Indicate a regular mind-body practice (e.g., yoga, meditation) in the past six months
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Cousins Center for Psychoneuroimmunology, UCLA
Los Angeles, California, 90095, United States
Related Publications (3)
Hinkin CH, Barclay TR, Castellon SA, Levine AJ, Durvasula RS, Marion SD, Myers HF, Longshore D. Drug use and medication adherence among HIV-1 infected individuals. AIDS Behav. 2007 Mar;11(2):185-94. doi: 10.1007/s10461-006-9152-0.
PMID: 16897351BACKGROUNDCreswell JD, Way BM, Eisenberger NI, Lieberman MD. Neural correlates of dispositional mindfulness during affect labeling. Psychosom Med. 2007 Jul-Aug;69(6):560-5. doi: 10.1097/PSY.0b013e3180f6171f. Epub 2007 Jul 18.
PMID: 17634566BACKGROUNDCreswell JD, Myers HF, Cole SW, Irwin MR. Mindfulness meditation training effects on CD4+ T lymphocytes in HIV-1 infected adults: a small randomized controlled trial. Brain Behav Immun. 2009 Feb;23(2):184-8. doi: 10.1016/j.bbi.2008.07.004. Epub 2008 Jul 19.
PMID: 18678242DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Hector F Myers, PhD
University of California, Los Angeles
- STUDY DIRECTOR
J. David Creswell, PhD
Cousins Center for Psychoneuroimmunology, UCLA
Study Design
- Study Type
- interventional
- Phase
- phase 2
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
January 14, 2008
First Posted
January 25, 2008
Study Start
June 1, 2005
Primary Completion
December 1, 2007
Study Completion
January 1, 2008
Last Updated
January 25, 2008
Record last verified: 2008-01