Altered Faecal Protease Activity in Irritable Bowel Syndrome Patients in China

NCT01060527 | Unknown

• 1 other identifier: xi'an JTU091202
• Study Type: observational
• Target: 60
• Locations: 0 countries
• Sites: N/A

Brief Summary

Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder haracterised by abdominal pain or discomfort associated with altered bowel habits,while the mechanism is still not understood.Recent advances have conceptualized the faecal supernatants of diarrhoea-predominant IBS have a substantially higher serine protease activity, while in china,almost no studies have reported about protease activity in IBS.

Conditions

Irritable Bowel Syndrome

Keywords

irritable bowel syndrome,protease activity,China

Study Arms (3)

IBS-D

IBS-C

Controll

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Outpatients in the second affiliated hospital of xi'an jiaotong university

You may qualify if:

• Patients fulfilling the Rome III criteria for IBS participated in the study -

You may not qualify if:

• Organic gastrointestinal disorders were excluded by detailed blood and stool analyses, serological assays and colonoscopy.

Sponsors & Collaborators

• Xi'an Jiaotong University: lead

MeSH Terms

Conditions

Irritable Bowel Syndrome

Condition Hierarchy (Ancestors)

Colonic Diseases, Functional; Colonic Diseases; Intestinal Diseases; Gastrointestinal Diseases; Digestive System Diseases

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: February 1, 2010
• First Posted: February 2, 2010
• Study Start: January 1, 2010
• Last Updated: February 2, 2010

Record last verified: 2010-01