NCT01057004

Brief Summary

EVITA should function as an idea supplier and should coordinate possible future studies. Other important tasks of the register are: (i) the establishment of recommendations for an optimal medicinal therapy (OMT) as well as for ICD- and CRT-treatment; (ii) the establishment of quality assurance measures, including monitoring of new therapy.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
4,560

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Feb 2009

Longer than P75 for all trials

Geographic Reach
1 country

11 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2009

Completed
12 months until next milestone

First Submitted

Initial submission to the registry

January 26, 2010

Completed
1 day until next milestone

First Posted

Study publicly available on registry

January 27, 2010

Completed
5.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2015

Completed
Last Updated

June 24, 2016

Status Verified

June 1, 2016

Enrollment Period

6.8 years

First QC Date

January 26, 2010

Last Update Submit

June 23, 2016

Conditions

Keywords

heart failure

Outcome Measures

Primary Outcomes (1)

  • Characteristics of consecutive patients with chronic cardiac insufficiency and an EF ≤ 40% in hospital daily routine within Germany

    Admission to Hospital and 12 months thereafter

Secondary Outcomes (9)

  • Specification of the medical therapy according to the guidelines

    Admission to hospital and 12 months thereafter

  • Monitoring of innovations of new therapy possibilities once these are introduced on the market

    Admission to Hospital and 12 months thereafter

  • Specifications of implantable devices including ICD and CRT as well as the procedure of implantation and the success of the surgical intervention

    Admission to Hospital and 12 months thereafter

  • Further interventions during clinical stay, after the index-event

    Index hospital stay

  • Hospital mortality and non-fatal complications

    Index hospital stay

  • +4 more secondary outcomes

Study Arms (1)

all patients

chronical heart failure and EF ≤ 40 %

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

primary care clinic

You may qualify if:

  • chronical heart failure
  • EF ≤ 40 %

You may not qualify if:

  • no informed consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (11)

Universitätsklinikum Heidelberg

Heidelberg, Baden-Wurttemberg, 69120, Germany

Location

Zentralklinikum Augsburg

Augsburg, Bavaria, 86156, Germany

Location

Klinikum Coburg

Coburg, Bavaria, 96450, Germany

Location

Klinikum Nürnberg

Nuremberg, Bavaria, 90471, Germany

Location

Universitätsklinikum Würzburg

Würzburg, Bavaria, 97080, Germany

Location

Klinikum Links der Weser Bremen

Bremen, City state Bremen, 28277, Germany

Location

Universitätsklinik Rostock

Rostock, Mecklenburg-Vorpommern, 18057, Germany

Location

Klinikum Lippe-Detmold

Detmold, North Rhine-Westphalia, 32756, Germany

Location

Universitätsklinikum Essen (Klinik für Kardiologie)

Essen, North Rhine-Westphalia, 45122, Germany

Location

Elisabeth - Krankenhaus (Kardiologie) Essen

Essen, North Rhine-Westphalia, 45138, Germany

Location

Universitätsklinikum des Saarlandes

Homburg/Saar, Saarland, 66421, Germany

Location

MeSH Terms

Conditions

Heart Failure

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular Diseases

Study Officials

  • Jochen Senges, MD

    Stiftung Institut für Herzinfarktforschung

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 26, 2010

First Posted

January 27, 2010

Study Start

February 1, 2009

Primary Completion

December 1, 2015

Study Completion

December 1, 2015

Last Updated

June 24, 2016

Record last verified: 2016-06

Data Sharing

IPD Sharing
Will not share

Locations