NCT01048281

Brief Summary

Our research of the biology of upper gastrointestinal cancers involves the study of tissue samples and cells from biopsies of persons with gastric or esophageal cancer or blood samples from upper gastrointestinal cancer patients and persons at high inherited risk for these cancers. We hope to learn the role genes and proteins play in the development of gastric and esophageal cancer.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
883mo left

Started Aug 2002

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress25%
Aug 2002Jan 2099

Study Start

First participant enrolled

August 1, 2002

Completed
7.5 years until next milestone

First Submitted

Initial submission to the registry

January 11, 2010

Completed
2 days until next milestone

First Posted

Study publicly available on registry

January 13, 2010

Completed
89 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2099

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2099

Last Updated

December 18, 2025

Status Verified

December 1, 2025

Enrollment Period

96.5 years

First QC Date

January 11, 2010

Last Update Submit

December 17, 2025

Conditions

Stomach CancerGastric (Stomach) CancerGastro-Esophageal(GE) Junction CancerEsophageal CancerGastrointestinal Stromal Tumor (GIST)

Outcome Measures

Primary Outcomes (2)

  • p53 activity by routine pathologic analysis

    time of collection

  • NER activity by routine pathologic analysis

    time of collection

Interventions

Blood drawPROCEDURE
Tissue tumor biopsyPROCEDURE

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Adults with gastric or esophageal cancer

You may qualify if:

  • Over 18
  • Diagnosed with gastric or esophageal cancer OR at an increased hereditary risk for upper GI cancer

You may not qualify if:

  • Under 18
  • No family or personal history of gastric or esophageal cancer

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Stanford University School of Medicine

Stanford, California, 94305, United States

RECRUITING

Biospecimen

Retention: SAMPLES WITH DNA

blood, tumor

MeSH Terms

Conditions

Stomach NeoplasmsEsophageal NeoplasmsGastrointestinal Stromal Tumors

Interventions

Blood Specimen Collection

Condition Hierarchy (Ancestors)

Gastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesGastrointestinal DiseasesStomach DiseasesHead and Neck NeoplasmsEsophageal DiseasesNeoplasms, Connective TissueNeoplasms, Connective and Soft TissueNeoplasms by Histologic Type

Intervention Hierarchy (Ancestors)

Specimen HandlingClinical Laboratory TechniquesDiagnostic Techniques and ProceduresDiagnosisPuncturesSurgical Procedures, OperativeInvestigative Techniques

Study Officials

  • James M Ford

    Stanford University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Meredith Mills

CONTACT

(650) 724-5223bluett@stanford.edu

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 11, 2010

First Posted

January 13, 2010

Study Start

August 1, 2002

Primary Completion (Estimated)

January 1, 2099

Study Completion (Estimated)

January 1, 2099

Last Updated

December 18, 2025

Record last verified: 2025-12

Locations

US(1)