Plain Magnetic Resonance (MR) in the Assessment of Patients With Acute Abdomen
Assessment of Patients With Nontraumatic Acute Abdominal Pain With Plain MR of the Abdomen - a Comparison With CT
1 other identifier
interventional
N/A
1 country
1
Brief Summary
At present, CT is the gold standard in the assessment of patients with acute abdomen. Yet, one CT of the abdomen exposes patients to a radiation dose equivalent to several years of background radiation. MR can be expected to yield the same information without ionizing radiation, but tends to be more time consuming. In this study, patients with nontraumatic acute abdominal pain referred to CT of the abdomen by the department of surgery will also have performed an additional MR scan covering the entire abdomen with few fast imaging sequences in approximately 15min. CT is the diagnostic test. The MR scan is only used for scientific purposes. It will be evaluated by a radiologist blinded for the results of the CT scan. Fourteen days after admission, a final diagnosis is established based on clinical, peroperative, pathological and lab. findings. The performance of CT and MR will then be compared. The investigators hypothesize that MR can provide a diagnostic accuracy comparable to CT.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
Started Oct 2011
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
January 6, 2010
CompletedFirst Posted
Study publicly available on registry
January 7, 2010
CompletedStudy Start
First participant enrolled
October 1, 2011
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 1, 2012
CompletedStudy Completion
Last participant's last visit for all outcomes
October 1, 2012
CompletedJanuary 31, 2017
January 1, 2017
11 months
January 6, 2010
January 29, 2017
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
diagnostic accuracy of CT vs. MR
14 days
Interventions
axial and coronal free breathing HASTE sequences 3D T1 weighted gradient echo breathhold
Eligibility Criteria
You may qualify if:
- Signed informed consent form
- Age \> 18 years old
- Nontraumatic acute abdomen
- Weight \< 120kg
- Can keep apnoea for 15s
- Surgeon in charge considers patient fit for participation in study
You may not qualify if:
- Contraindications of MRI
- Suspicion of acute vascular disease
- Severe cardial or pulmonal insufficiency
- Pregnancy
- Untreated psychiatric illness
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Koege Sygehus
Koege, DK4600, Denmark
Related Publications (1)
Stoker J. Magnetic resonance imaging and the acute abdomen. Br J Surg. 2008 Oct;95(10):1193-4. doi: 10.1002/bjs.6378. No abstract available.
PMID: 18763236BACKGROUND
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Thomas Jørgensen, MD
Zealand University Hospital
- STUDY DIRECTOR
Jens Maier, MD
Zealand University Hospital
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- NONE
- Purpose
- DIAGNOSTIC
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- overlæge, radiologisk afdeling, Køge sygehus
Study Record Dates
First Submitted
January 6, 2010
First Posted
January 7, 2010
Study Start
October 1, 2011
Primary Completion
September 1, 2012
Study Completion
October 1, 2012
Last Updated
January 31, 2017
Record last verified: 2017-01