NCT01044147

Brief Summary

With over half of the US population currently overweight and 31% of adults now obese, the primary care setting may represent an important source of weight-loss support, in the interest of cardiovascular prevention. Yet, although the US Preventive Services task force recommends that physicians screen all adult patients for obesity and offer intensive counseling and behavioral interventions to promote sustained weight loss for obese adults, the recommendation has not been widely implemented. The Internet may help overcome many of the barriers that have prevented intensive obesity counseling in the clinical setting. The aim of this study is to examine whether Internet-based interventions for developing healthier lifestyles can improve preventive health care in a cost-effective manner.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
360

participants targeted

Target at P75+ for phase_2 obesity

Timeline
Completed

Started Apr 2010

Typical duration for phase_2 obesity

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 5, 2010

Completed
2 days until next milestone

First Posted

Study publicly available on registry

January 7, 2010

Completed
3 months until next milestone

Study Start

First participant enrolled

April 1, 2010

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2011

Completed
9 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2012

Completed
Last Updated

January 14, 2016

Status Verified

January 1, 2016

Enrollment Period

1.7 years

First QC Date

January 5, 2010

Last Update Submit

January 13, 2016

Conditions

Keywords

ObesityInternet

Outcome Measures

Primary Outcomes (1)

  • Change in body weight (Kg)

    1 year

Secondary Outcomes (8)

  • % obtaining >7% weight loss

    1 year

  • Change in BMI (kg/m2)

    1 year

  • Change in waist circumference

    1 year

  • Change in steps per day

    1 year

  • Change in health-related quality of life as measured by the RAND-36 PCS or MCS

    1 year

  • +3 more secondary outcomes

Study Arms (3)

VLM-S

EXPERIMENTAL

Participants in this arm receive "standard" lifestyle coaching, which is delivered on a specified schedule. They will also receive online information about evidence-based lifestyle goals and links to reputable resources for helping to achieve a healthy lifestyle.

Behavioral: VLM-S

VLM-M

EXPERIMENTAL

Participants in this arm receive "modulated" lifestyle coaching, where coaching frequency may be adjusted according to whether the participant is meeting program goals for program use and targeted behaviors. They will also receive online information about evidence-based lifestyle goals and links to reputable resources for helping to achieve a healthy lifestyle.

Behavioral: VLM-M

OGR

ACTIVE COMPARATOR

Participants in this arm will receive online information about evidence-based lifestyle goals and links to reputable resources for helping to achieve a healthy lifestyle, but not personalized lifestyle coaching.

Behavioral: OGR

Interventions

VLM-SBEHAVIORAL

Online program for weight loss - standard

VLM-S
VLM-MBEHAVIORAL

Online program for weight loss - modulated

VLM-M
OGRBEHAVIORAL

Online program for weight loss - resources

OGR

Eligibility Criteria

Age21 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Obese (BMI \> 30kg/meters squared)
  • Age 21-75
  • Receives primary care at a participating primary care clinic in the Pittsburgh, PA area

You may not qualify if:

  • Primary care physician determination that moderate physical activity is not safe or appropriate for the patient
  • Pregnancy
  • Planned pregnancy in the next 2 years
  • Current breast-feeding
  • Bariatric surgery in the past 2 years
  • Planned bariatric surgery in the next 2 years
  • Edematous state that interferes with body weight assessment
  • Health condition that is likely to influence body weight
  • Heart attack within the past 3 months
  • Regular use of prescription medication that is likely to influence body weight
  • participation during the past year in either of the pilot programs for this study
  • perceived lack of basic computer or Internet skills
  • Inability to learn adequately from English language audio-recorded materials
  • Lack of access to a scale
  • Inability to attend an Orientation session

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Pittsburgh

Pittsburgh, Pennsylvania, 15213, United States

Location

Related Publications (1)

  • Diabetes Prevention Program (DPP) Research Group. The Diabetes Prevention Program (DPP): description of lifestyle intervention. Diabetes Care. 2002 Dec;25(12):2165-71. doi: 10.2337/diacare.25.12.2165.

    PMID: 12453955BACKGROUND

MeSH Terms

Conditions

Obesity

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Kathleen M McTigue, MD, MS, MPH

    University of Pittsburgh

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assitant Professor

Study Record Dates

First Submitted

January 5, 2010

First Posted

January 7, 2010

Study Start

April 1, 2010

Primary Completion

December 1, 2011

Study Completion

September 1, 2012

Last Updated

January 14, 2016

Record last verified: 2016-01

Locations