The Effects of Gum Chewing on Energy Intake and Expenditure

NCT01043471 | Completed

• 1 other identifier: H-2007-0342
• Study Type: interventional
• Target: 31
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to determine if chewing gum increases energy expenditure and decreases food intake.

Conditions

Obesity

Keywords

Obesity

Outcome Measures

Primary Outcomes (1)

• Change in body composition

  Baseline and end of study (6 weeks)

Study Arms (2)

Chewing gum

EXPERIMENTAL

Other: Chewing gum

Water

PLACEBO COMPARATOR

Other: Water

Interventions

Chewing gum OTHER

Subjects were instructed to chew gum at least 6 times a day in an effort to reduce snacking.

Chewing gum

Water OTHER

Subjects were instructed to drink 8 oz of water at least 6 times a day in an effort to reduce snacking.

Water

Eligibility Criteria

• Age: 18 Years - 38 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• BMI 27-37, between the ages of 18 and 38

You may not qualify if:

• History of chronic disease (e.g. liver, kidney, or heart disease, or diabetes)
• Medications that affect energy expenditure, appetite, or body composition (e.g. antidepressants, beta blockers, antipsychotic, or weight loss medications)
• A history of irregular menstrual cycles in women (indication of onset of menopause or other metabolic disturbances such as polycystic ovary syndrome)
• A history of phenylketonuria (PKU)
• Symptoms of depression
• A history of eating disorders
• Concurrent participation in a weight loss program
• Cigarette smoking or other tobacco use
• Jaw problems such as temporomandibular joint disorder (TMJ)
• Allergies to any of the common components in gum (sweeteners, mint flavors, etc)
• Heavy gum chewing prior to study ( \> 3 times per week)
• Pregnancy or lactation.

Sponsors & Collaborators

• University of Wisconsin, Madison: lead
• The Obesity Society: collaborator

Study Sites (1)

University of Wisconsin-Madison

Madison, Wisconsin, 53792, United States

Location

MeSH Terms

Conditions

Obesity

Interventions

Chewing Gum; Water

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Plant Gums; Biopolymers; Polymers; Macromolecular Substances; Polysaccharides; Carbohydrates; Plant Exudates; Biological Products; Complex Mixtures; Candy; Food; Diet, Food, and Nutrition; Physiological Phenomena; Food and Beverages; Hydroxides; Alkalies; Inorganic Chemicals; Anions; Ions; Electrolytes; Oxides; Oxygen Compounds

Study Officials

• Leah D Whigham, PhD

  Board of Regents of the University of Wisconsin System

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 15, 2009
• First Posted: January 6, 2010
• Study Start: September 1, 2008
• Study Completion: January 1, 2011
• Last Updated: October 8, 2015

Record last verified: 2015-10

Locations

US (1)